Interactor 1: HSPA9 (P38646)
Stress-70 protein, mitochondrial (EC 3.6.4.10) (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9) (Heat shock protein family A member 9) (Mortalin) (MOT) (Peptide-binding protein 74) (PBP74)
Gene: HSPA9

Interactor 2: GRPE1 (Q9HAV7)
GrpE protein homolog 1, mitochondrial (HMGE) (Mt-GrpE#1)
Gene: GRPEL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.962

The method score is based on:

Property Details
Experiments 28514442, 33961781, 31839598, 30021884, 33957083, 37071682, 35575683
Identification Methods affinity chromatography technology, cross-linking study, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains GrpE~HSP70
Common GO terms GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005744 - TIM23 mitochondrial import inner membrane translocase complex
GO:0005759 - mitochondrial matrix
GO:0006886 - intracellular protein transport
and 1 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 679
Hs

1 217
+ Mm
+ Sc
+ Sc
+ Ec
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025