HitPredict

Interactor 1: CALM1 (P0DP29)
Calmodulin-1
Gene: CALM1

Interactor 2: KCNN2 (P70604)
Small conductance calcium-activated potassium channel protein 2 (SK2) (SKCa 2) (SKCa2) (KCa2.2)
Gene: KCNN2

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.866

Property	Details
Experiments	15130477, 11323678, 22579256
Identification Methods	x-ray crystallography, isothermal titration calorimetry, classical fluorescence spectroscopy, cosedimentation in solution
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	CaMBD~EF-hand_7
Common GO terms	GO:0019904 - protein domain specific binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 149 Rn			1 580
+	Rn
		110754 CALM1_RAT (1-149): 1.99e-56: 174: 100.00		H6VQ94_RAT (1-557): 0: 558: 99.46
+	Rn
		292479 CALM1_RAT (1-149): 1.99e-56: 174: 100.00		KCNQ2_RAT (55-570): 2.15e-101: 327: 15.04
+	Hs
		484086 CALM3_HUMAN (1-149): 1.99e-56: 174: 100.00		KCNQ1_HUMAN (27-455): 7.08e-101: 321: 15.32
+	Dm
		825623 CALL_DROME (3-149): 9.23e-57: 175: 66.67		Q5PXF9_DROME (83-453): 4.88e-86: 286: 16.32
+	Dm
		906676 CALM_DROME (1-149): 5.63e-56: 173: 97.99		Q5PXF9_DROME (83-453): 4.88e-86: 286: 16.32