HitPredict

Interactor 1: HXB7 (P09629)
Homeobox protein Hox-B7 (Homeobox protein HHO.C1) (Homeobox protein Hox-2C)
Gene: HOXB7

Interactor 2: XRCC5 (P13010)
X-ray repair cross-complementing protein 5 (EC 3.6.4.-) (86 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 2) (ATP-dependent DNA helicase II 80 kDa subunit) (CTC box-binding factor 85 kDa subunit) (CTC85) (CTCBF) (DNA repair protein XRCC5) (Ku80) (Ku86) (Lupus Ku autoantigen protein p86) (Nuclear factor IV) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining))
Gene: XRCC5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.59	0.60	0.597

Property	Details
Experiments	17308091
Identification Methods	affinity chromatography technology, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 217 Hs			1 732
+	Hs
		559279 PDX1_HUMAN (13-217): 3.29e-36: 130: 27.88		XRCC5_HUMAN (1-732): 0: 757: 100.00
+	Hs
		478309 HXC4_HUMAN (3-211): 1.03e-27: 107: 32.16		XRCC5_HUMAN (1-732): 0: 757: 100.00
+	Hs
		484811 HXB7_HUMAN (1-208): 9.21e-59: 186: 100.00		XRCC6_HUMAN (3-609): 7.6e-142: 430: 14.49
+	Dm
		627224 DLL_DROME (24-205): 7.21e-44: 151: 28.27		Q9I7M8_DROME (4-682): 2.57e-143: 437: 20.40
+	Hs
		557978 PDX1_HUMAN (13-217): 3.29e-36: 130: 27.88		XRCC6_HUMAN (3-609): 7.6e-142: 430: 14.49
+	Hs
		478279 HXD4_HUMAN (3-197): 2.4e-35: 127: 34.60		XRCC6_HUMAN (3-609): 7.6e-142: 430: 14.49
+	Hs
		478308 HXC4_HUMAN (3-211): 1.03e-27: 107: 32.16		XRCC6_HUMAN (3-609): 7.6e-142: 430: 14.49
+	Dm
		627200 DLL_DROME (24-205): 7.21e-44: 151: 28.27		KU70_DROME (4-573): 2.72e-107: 341: 12.38