HitPredict

Interactor 1: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Interactor 2: RC3H1 (Q5TC82)
Roquin-1 (Roquin) (EC 2.3.2.27) (RING finger and C3H zinc finger protein 1) (RING finger and CCCH-type zinc finger domain-containing protein 1) (RING finger protein 198)
Gene: RC3H1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30209976
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0035198 - miRNA binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 372 Hs			1 1133
+	Hs
		172125 HNRDL_HUMAN (2-282): 5.24e-72: 232: 33.56		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		909600 ROA3_HUMAN (7-202): 1.05e-56: 191: 85.71		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		650802 ROA2_HUMAN (1-320): 2.13e-56: 189: 58.44		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		1215826 PABP3_HUMAN (6-193): 7.32e-37: 142: 17.90		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		1215787 ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		1120192 HNRPD_HUMAN (2-99): 4.16e-18: 86.4: 24.00		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		214302 MSI1H_HUMAN (91-188): 7.27e-17: 82.9: 28.57		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		1101989 PABP4_HUMAN (102-193): 4.58e-15: 78.7: 15.05		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		1215760 MSI2H_HUMAN (2-87): 1.64e-15: 78.7: 36.05		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		172224 HNRDL_HUMAN (2-282): 5.24e-72: 232: 33.56		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		485423 ROA1_HUMAN (1-372): 6.83e-64: 210: 100.00		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		650965 ROA2_HUMAN (1-320): 2.13e-56: 189: 58.44		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		1432507 PABP3_HUMAN (6-193): 7.32e-37: 142: 17.90		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		1406854 ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		1120345 HNRPD_HUMAN (2-99): 4.16e-18: 86.4: 24.00		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		214341 MSI1H_HUMAN (91-188): 7.27e-17: 82.9: 28.57		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		1102102 PABP4_HUMAN (102-193): 4.58e-15: 78.7: 15.05		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		1387472 MSI2H_HUMAN (2-87): 1.64e-15: 78.7: 36.05		RC3H2_HUMAN (1-1107): 0: 1494: 51.72