HitPredict

Interactor 1: ROA2 (P22626)
Heterogeneous nuclear ribonucleoproteins A2/B1 (hnRNP A2/B1)
Gene: HNRNPA2B1

Interactor 2: RC3H1 (Q5TC82)
Roquin-1 (Roquin) (EC 2.3.2.27) (RING finger and C3H zinc finger protein 1) (RING finger and CCCH-type zinc finger domain-containing protein 1) (RING finger protein 198)
Gene: RC3H1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	26170170, 30209976
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003730 - mRNA 3'-UTR binding GO:0035198 - miRNA binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 353 Hs			1 1133
+	Hs
		172125 HNRDL_HUMAN (12-292): 9.85e-66: 215: 33.45		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		214302 MSI1H_HUMAN (3-341): 3.22e-62: 204: 28.77		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		1215760 MSI2H_HUMAN (1-341): 2.05e-56: 188: 28.15		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		550320 PABP1_HUMAN (12-200): 3.6e-38: 146: 18.95		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		1120192 HNRPD_HUMAN (22-191): 3.36e-37: 138: 41.77		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		909600 ROA3_HUMAN (3-103): 3.4e-17: 83.6: 33.66		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		485200 ROA1_HUMAN (3-96): 4.34e-17: 83.2: 31.92		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		1101989 PABP4_HUMAN (109-200): 1.4e-15: 79.8: 16.13		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		1215826 PABP3_HUMAN (102-200): 7.72e-13: 71.3: 16.00		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		172224 HNRDL_HUMAN (12-292): 9.85e-66: 215: 33.45		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		650965 ROA2_HUMAN (1-353): 7.92e-64: 208: 100.00		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		214341 MSI1H_HUMAN (3-341): 3.22e-62: 204: 28.77		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		1387472 MSI2H_HUMAN (1-341): 2.05e-56: 188: 28.15		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		550473 PABP1_HUMAN (12-200): 3.6e-38: 146: 18.95		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		1120345 HNRPD_HUMAN (22-191): 3.36e-37: 138: 41.77		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		485423 ROA1_HUMAN (3-96): 4.34e-17: 83.2: 31.92		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		1102102 PABP4_HUMAN (109-200): 1.4e-15: 79.8: 16.13		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		1432507 PABP3_HUMAN (102-200): 7.72e-13: 71.3: 16.00		RC3H2_HUMAN (1-1107): 0: 1494: 51.72