HitPredict

Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: SRC (P12931)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 0.60 0.727

The method score is based on:

Property Details
Experiments 11032808, 15466214, 15027889, 24728074, 15062576, 12933816
Identification Methods affinity chromatography technology, two hybrid, pull down, anti tag coimmunoprecipitation, fluorescence polarization spectroscopy
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005102 - signaling receptor binding
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
and 5 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 920
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024