HitPredict

Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: CDN2A (P42771)
Cyclin-dependent kinase inhibitor 2A (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (Multiple tumor suppressor 1) (MTS-1) (p16-INK4a) (p16-INK4) (p16INK4A)
Gene: CDKN2A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23449888
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008285 - negative regulation of cell population proliferation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 920 Hs			1 156
+	Hs
		487686 ANDR_HUMAN (1-920): 0: 966: 100.00		EHMT2_HUMAN (4-114): 3.84e-29: 113: 24.11
+	Hs
		370465 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		EHMT1_HUMAN (4-121): 1.19e-30: 117: 19.33
+	Hs
		370223 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		EHMT2_HUMAN (4-114): 3.84e-29: 113: 24.11
+	Hs
		795592 NR4A2_HUMAN (307-905): 2.74e-119: 377: 16.72		CDN2D_HUMAN (12-134): 6.5e-45: 146: 49.19
+	Hs
		93993 F1D8N6_HUMAN (307-905): 2.74e-119: 377: 16.72		CDN2D_HUMAN (12-134): 6.5e-45: 146: 49.19
+	Hs
		257541 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		ANR17_HUMAN (69-147): 2.99e-19: 85.1: 20.25
+	Hs
		369847 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		POTEE_HUMAN (49-152): 2.11e-18: 82.7: 14.82
+	Hs
		369957 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		ANKH1_HUMAN (68-155): 3.32e-18: 82.3: 19.32
+	Hs
		377694 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		EHMT1_HUMAN (4-121): 1.19e-30: 117: 19.33
+	Hs
		370389 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		TANC1_HUMAN (56-154): 1.3e-14: 71.9: 21.00
+	Hs
		370687 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		KDIS_HUMAN (86-156): 1.81e-12: 65.8: 19.48
+	Hs
		370593 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		RAI14_HUMAN (1-64): 1.97e-11: 62.7: 21.21
+	Hs
		60386 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		POTEF_HUMAN (1-130): 1.26e-29: 115: 19.55
+	Hs
		1269380 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		EHMT2_HUMAN (4-114): 3.84e-29: 113: 24.11
+	Hs
		257543 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		ANR17_HUMAN (69-147): 2.99e-19: 85.1: 20.25
+	Hs
		377037 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		POTEJ_HUMAN (49-152): 1.44e-18: 83.1: 13.89
+	Hs
		257677 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		ANR17_HUMAN (69-147): 2.99e-19: 85.1: 20.25
+	Hs
		474887 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		POTEJ_HUMAN (49-152): 1.44e-18: 83.1: 13.89
+	Hs
		377204 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		DAPK1_HUMAN (49-155): 4.06e-14: 70.4: 22.02
+	Hs
		377700 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		TANC2_HUMAN (1-99): 3.54e-10: 59.3: 21.57