HitPredict

Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: SMRC2 (Q8TAQ2)
SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2)
Gene: SMARCC2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	28611094, 33640491, 34585037
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005654 - nucleoplasm GO:0032991 - protein-containing complex GO:0045597 - positive regulation of cell differentiation GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 920 Hs			1 1214
+	Hs
		487644 ANDR_HUMAN (1-920): 0: 966: 100.00		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Hs
		377515 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		SMRC2_HUMAN (1-1203): 0: 992: 100.00
+	Hs
		377556 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Hs
		487510 ANDR_HUMAN (1-920): 0: 966: 100.00		MYSM1_HUMAN (276-523): 7.61e-53: 202: 22.96
+	Hs
		231976 ANDR_HUMAN (1-920): 0: 966: 100.00		KDM1A_HUMAN (253-543): 1.97e-43: 173: 15.00
+	Mm
		580483 ANDR_MOUSE (1-920): 0: 933: 84.30		KDM1A_MOUSE (254-543): 9.03e-44: 174: 15.05
+	Hs
		487879 ANDR_HUMAN (1-920): 0: 966: 100.00		NCOR2_HUMAN (588-1208): 2.06e-32: 139: 14.22
+	Hs
		261380 ANDR_HUMAN (1-920): 0: 966: 100.00		NCOR1_HUMAN (597-1154): 8.84e-32: 137: 10.86
+	Hs
		487832 ANDR_HUMAN (1-920): 0: 966: 100.00		ZMIZ1_HUMAN (968-1213): 2.22e-11: 70.8: 16.53
+	Hs
		487809 ANDR_HUMAN (1-920): 0: 966: 100.00		RERE_HUMAN (759-1212): 1.19e-09: 65: 16.17
+	Hs
		487596 ANDR_HUMAN (1-920): 0: 966: 100.00		KMT2C_HUMAN (650-1128): 8.15e-09: 62.4: 8.57
+	Hs
		231951 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		KDM1A_HUMAN (253-543): 1.97e-43: 173: 15.00
+	Hs
		370824 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		NCOR2_HUMAN (588-1208): 2.06e-32: 139: 14.22
+	Hs
		261369 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		NCOR1_HUMAN (597-1154): 8.84e-32: 137: 10.86
+	Hs
		231953 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		KDM1A_HUMAN (253-543): 1.97e-43: 173: 15.00
+	Hs
		377839 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		NCOR2_HUMAN (588-1208): 2.06e-32: 139: 14.22
+	Hs
		795610 NR4A2_HUMAN (307-905): 2.74e-119: 377: 16.72		NCOR2_HUMAN (588-1208): 2.06e-32: 139: 14.22
+	Hs
		261370 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		NCOR1_HUMAN (597-1154): 8.84e-32: 137: 10.86
+	Hs
		370040 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		KMT2C_HUMAN (650-1128): 8.15e-09: 62.4: 8.57
+	Mm
		70893 ESR1_MOUSE (378-904): 2.5e-129: 403: 21.30		EP300_MOUSE (885-1214): 8.74e-09: 62.4: 13.78