HitPredict

Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: REQU (Q92785)
Zinc finger protein ubi-d4 (Apoptosis response zinc finger protein) (BRG1-associated factor 45D) (BAF45D) (D4, zinc and double PHD fingers family 2) (Protein requiem)
Gene: DPF2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	28611094, 33640491, 34585037, 35785414
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 920 Hs			1 391
+	Hs
		487634 ANDR_HUMAN (1-920): 0: 966: 100.00		DPF1_HUMAN (1-385): 1.2e-87: 272: 56.25
+	Hs
		487845 ANDR_HUMAN (1-920): 0: 966: 100.00		TRI33_HUMAN (6-389): 8.72e-52: 188: 12.66
+	Hs
		487382 ANDR_HUMAN (1-920): 0: 966: 100.00		CHD3_HUMAN (43-382): 1.44e-49: 181: 13.23
+	Hs
		487438 ANDR_HUMAN (1-920): 0: 966: 100.00		CHD4_HUMAN (32-382): 5.17e-44: 165: 12.73
+	Hs
		487739 ANDR_HUMAN (1-920): 0: 966: 100.00		KDM5D_HUMAN (122-391): 6.33e-37: 144: 18.75
+	Hs
		487351 ANDR_HUMAN (1-920): 0: 966: 100.00		KMT2A_HUMAN (80-388): 8.66e-36: 141: 14.38
+	Hs
		487688 ANDR_HUMAN (1-920): 0: 966: 100.00		NSD1_HUMAN (101-375): 8.5e-35: 138: 17.97
+	Hs
		487816 ANDR_HUMAN (1-920): 0: 966: 100.00		KDM5B_HUMAN (127-391): 4.25e-34: 136: 16.11
+	Hs
		170224 ANDR_HUMAN (1-920): 0: 966: 100.00		TIF1A_HUMAN (25-391): 1.7e-32: 131: 14.06
+	Hs
		152579 ANDR_HUMAN (1-920): 0: 966: 100.00		KMT2D_HUMAN (241-382): 8.36e-23: 102: 30.77
+	Hs
		487596 ANDR_HUMAN (1-920): 0: 966: 100.00		KMT2C_HUMAN (266-376): 2.95e-09: 61.3: 22.22
+	Hs
		370135 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		REQU_HUMAN (1-391): 1.89e-101: 307: 100.00
+	Hs
		369621 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		CHD4_HUMAN (32-382): 5.17e-44: 165: 12.73
+	Hs
		370137 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		KAT6A_HUMAN (76-387): 3.75e-43: 162: 26.48
+	Hs
		369449 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		KMT2A_HUMAN (80-388): 8.66e-36: 141: 14.38
+	Hs
		370224 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		NSD1_HUMAN (101-375): 8.5e-35: 138: 17.97
+	Hs
		170202 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		TIF1A_HUMAN (25-391): 1.7e-32: 131: 14.06
+	Hs
		152573 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		KMT2D_HUMAN (241-382): 8.36e-23: 102: 30.77
+	Hs
		369044 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		KDM5A_HUMAN (309-375): 1.26e-20: 96.4: 35.82
+	Hs
		370040 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		KMT2C_HUMAN (266-376): 2.95e-09: 61.3: 22.22