HitPredict

Interactor 1: HLAC (P10321)
HLA class I histocompatibility antigen, C alpha chain (HLA-C) (HLA-Cw) (Human leukocyte antigen C)
Gene: HLA-C

Interactor 2: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 366 Hs			1 196
+	Hs
		382382 HLAA_HUMAN (1-365): 1.85e-176: 496: 81.37		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		382373 HLAA_HUMAN (1-365): 1.85e-176: 496: 81.37		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		382381 HLAA_HUMAN (1-365): 1.85e-176: 496: 81.37		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		382288 HLAA_HUMAN (1-365): 1.85e-176: 496: 81.37		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		382270 HLAA_HUMAN (1-365): 1.85e-176: 496: 81.37		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		382389 HLAA_HUMAN (1-365): 1.85e-176: 496: 81.37		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		382370 HLAA_HUMAN (1-365): 1.85e-176: 496: 81.37		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		382371 HLAA_HUMAN (1-365): 1.85e-176: 496: 81.37		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		382296 HLAA_HUMAN (1-365): 1.85e-176: 496: 81.37		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		120272 HLAA_HUMAN (1-365): 1.85e-176: 496: 81.37		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98
+	Hs
		354401 HLAB_HUMAN (1-363): 6.17e-157: 446: 85.40		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		488185 HLAC_HUMAN (1-366): 8.9e-155: 441: 100.00		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		488182 HLAC_HUMAN (1-366): 8.9e-155: 441: 100.00		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		488115 HLAC_HUMAN (1-366): 8.9e-155: 441: 100.00		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		436130 HLAC_HUMAN (1-366): 8.9e-155: 441: 100.00		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		488178 HLAC_HUMAN (1-366): 8.9e-155: 441: 100.00		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		488180 HLAC_HUMAN (1-366): 8.9e-155: 441: 100.00		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		570315 HLAG_HUMAN (1-339): 2.59e-152: 434: 79.35		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49