HitPredict

Interactor 1: HLAC (P10321)
HLA class I histocompatibility antigen, C alpha chain (HLA-C) (HLA-Cw) (Human leukocyte antigen C)
Gene: HLA-C

Interactor 2: DRB5 (Q30154)
HLA class II histocompatibility antigen, DR beta 5 chain (DR beta-5) (DR2-beta-2) (Dw2) (MHC class II antigen DRB5)
Gene: HLA-DRB5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains C1-set~C1-set, C1-set~MHC_II_beta
Common GO terms GO:0000139 - Golgi membrane
GO:0002250 - adaptive immune response
GO:0005886 - plasma membrane
GO:0012507 - ER to Golgi transport vesicle membrane
GO:0042605 - peptide antigen binding
and 2 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 366
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024