Protein: LOXE3
Hydroperoxide isomerase ALOXE3 (Epidermis-type lipoxygenase 3) (Epidermal LOX-3) (e-LOX-3) (eLOX-3) (Hydroperoxy dehydratase ALOXE3) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152) (Hydroperoxy icosatetraenoate isomerase) (EC 5.4.4.7)

Gene: LOXE3, ALOXE3
Organism: Homo sapiens
Interactions: 51
UniProt ID: Q9BYJ1

Gene Ontology (top 5):
GO:0005506 - iron ion binding
GO:0005829 - cytosol
GO:0006665 - sphingolipid metabolic process
GO:0016020 - membrane
GO:0016702 - oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

870190

GLIP1
Glioma pathogenesis-related protein 1

3

0

High-throughput

0.634

High

557454

SRC
Proto-oncogene tyrosine-protein kinase Src

2

6

High-throughput

0.628

High

1204544

HERC4
Probable E3 ubiquitin-protein ligase HERC4

2

1

High-throughput

0.628

High

1418696

EDEM3
ER degradation-enhancing alpha-mannosidase-like protein 3

2

1

High-throughput

0.628

High

276626

LX12B
Arachidonate 12-lipoxygenase, 12R-type

1

3

Small-scale

0.618

High

292303

B3GL1
UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1

3

1

High-throughput

0.609

High

1271218

DPPA4
Developmental pluripotency-associated protein 4

3

1

High-throughput

0.609

High

537848

HSP7C
Heat shock cognate 71 kDa protein

2

0

High-throughput

0.602

High

1339434

NBEA
Neurobeachin

2

0

High-throughput

0.602

High

1366774

NECT2
Nectin-2

2

0

High-throughput

0.602

High

1418700

KTU
Protein kintoun

2

0

High-throughput

0.602

High

1193378

GLYR1
Cytokine-like nuclear factor N-PAC

2

0

High-throughput

0.585

High

1400958

ALPK1
Alpha-protein kinase 1

2

0

High-throughput

0.576

High

1156052

ZIC1
Zinc finger protein ZIC 1

2

2

High-throughput

0.574

High

1178697

CCD27
Coiled-coil domain-containing protein 27

2

2

High-throughput

0.574

High

675658

TYY1
Transcriptional repressor protein YY1

2

3

High-throughput

0.553

High

890679

RGS3
Regulator of G-protein signaling 3

1

1

High-throughput

0.536

High

1252774

RN111
E3 ubiquitin-protein ligase Arkadia

1

2

High-throughput

0.536

High

1292969

AROS
Active regulator of SIRT1

1

1

High-throughput

0.536

High

1418702

PLK2
Serine/threonine-protein kinase PLK2

1

3

High-throughput

0.536

High

532935

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.513

High

1144458

NONO
Non-POU domain-containing octamer-binding protein

1

0

High-throughput

0.513

High

1315989

NRSN1
Neurensin-1

1

0

High-throughput

0.513

High

1418704

AAKG2
5'-AMP-activated protein kinase subunit gamma-2

1

0

High-throughput

0.513

High

213428

ZSC12
Zinc finger and SCAN domain-containing protein 12

2

1

High-throughput

0.504

High

420261

IFNA4
Interferon alpha-4

1

1

High-throughput

0.489

High

1094524

ZN154
Zinc finger protein 154

1

1

High-throughput

0.489

High

1292339

ZC3C1
Zinc finger C3HC-type protein 1

1

1

High-throughput

0.489

High

1293851

SFR1
Swi5-dependent recombination DNA repair protein 1 homolog

1

1

High-throughput

0.489

High

1418697

GALT9
Polypeptide N-acetylgalactosaminyltransferase 9

1

1

High-throughput

0.489

High

1418698

TB22B
TBC1 domain family member 22B

1

1

High-throughput

0.489

High

1418703

DAPLE
Protein Daple

1

2

High-throughput

0.489

High

1418705

HOOK1
Protein Hook homolog 1

1

1

High-throughput

0.489

High

1418706

RNF6
E3 ubiquitin-protein ligase RNF6

1

5

High-throughput

0.489

High

889936

VEGFB
Vascular endothelial growth factor B

1

0

High-throughput

0.458

High

1386459

PKHB2
Pleckstrin homology domain-containing family B member 2

1

0

High-throughput

0.458

High

1367197

ESR2
Estrogen receptor beta

1

4

High-throughput

0.437

High

1288846

ZFHX4
Zinc finger homeobox protein 4

2

0

High-throughput

0.328

High

1244216

MORN3
MORN repeat-containing protein 3

2

0

High-throughput

0.324

High

783751

ZNF76
Zinc finger protein 76

2

0

High-throughput

0.316

High

231261

NDUS5
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5

1

0

High-throughput

0.279

Low

354250

ZBED1
E3 SUMO-protein ligase ZBED1

1

0

High-throughput

0.279

Low

576262

PO2F1
POU domain, class 2, transcription factor 1

1

0

High-throughput

0.279

Low

1124110

RCAN2
Calcipressin-2

1

0

High-throughput

0.279

Low

1204676

BEX5
Protein BEX5

1

0

High-throughput

0.279

Low

1315311

UBAD2
UBA-like domain-containing protein 2

1

0

High-throughput

0.279

Low

1322722

F177A
Protein FAM177A1

1

0

High-throughput

0.279

Low

1372492

WNT8B
Protein Wnt-8b

1

0

High-throughput

0.279

Low

1418701

TLR7
Toll-like receptor 7

1

0

High-throughput

0.279

Low

937892

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.249

Low

1418699

CT096
Uncharacterized protein C20orf96

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025