HitPredict

Interactor 1: HSP72 (P10592)
Heat shock protein SSA2
Gene: SSA2

Interactor 2: VPS4 (P52917)
Vacuolar protein sorting-associated protein 4 (DOA4-independent degradation protein 6) (Protein END13) (Vacuolar protein-targeting protein 10)
Gene: VPS4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	19536198, 16429126
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0016887 - ATP hydrolysis activity
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 639 Sc			1 437
+	Sc
		491848 HSP71_YEAST (1-639): 0: 969: 97.04		VPS4_YEAST (1-437): 9.44e-127: 375: 100.00
+	Hs
		260119 HSP7C_HUMAN (2-639): 0: 948: 74.34		VPS4B_HUMAN (2-436): 2.84e-118: 354: 60.50
+	Rn
		926183 HSP7C_RAT (2-639): 0: 947: 74.34		KTNA1_RAT (54-434): 1e-111: 339: 38.14
+	Hs
		503823 HSP7C_HUMAN (2-639): 0: 948: 74.34		PRS8_HUMAN (7-384): 1.05e-104: 318: 26.30
+	Hs
		503834 HSP7C_HUMAN (2-639): 0: 948: 74.34		PRS10_HUMAN (3-383): 9.3e-100: 304: 25.77
+	Sc
		490492 HSP71_YEAST (1-639): 0: 969: 97.04		CDC48_YEAST (114-435): 6.42e-75: 252: 28.57
+	Sc
		491404 HSP71_YEAST (1-639): 0: 969: 97.04		TBP6_YEAST (123-437): 1.66e-72: 244: 44.34
+	Sc
		491314 HSP71_YEAST (1-639): 0: 969: 97.04		SAP1_YEAST (97-437): 3.31e-68: 234: 40.33
+	Hs
		503763 HSP7C_HUMAN (2-639): 0: 948: 74.34		TERA_HUMAN (114-434): 1.72e-74: 250: 29.55
+	Sc
		493330 HSP72_YEAST (1-639): 0: 935: 100.00		CDC48_YEAST (114-435): 6.42e-75: 252: 28.57
+	Sc
		494116 HSP72_YEAST (1-639): 0: 935: 100.00		TBP6_YEAST (123-437): 1.66e-72: 244: 44.34