Interactor 1: THIO (P10599)
Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP) (allergen Hom s Trx)
Gene: TXN
Interactor 2: CASP3 (P42574)
Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12]
Gene: CASP3
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.63 | 0.60 | 0.615 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17606900 |
| Identification Methods | anti bait coimmunoprecipitation, pull down, protease assay, fluorescence polarization spectroscopy, isothermal titration calorimetry |
| Interaction Type | direct interaction, physical association, protein cleavage |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
