Protein: SRMB
ATP-dependent RNA helicase SrmB (EC 3.6.4.13)

Gene: SRMB
Organism: Escherichia coli K-12
Interactions: 41
UniProt ID: P21507

Gene Ontology (top 5):
GO:0000027 - ribosomal large subunit assembly
GO:0003724 - RNA helicase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0008143 - poly(A) binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

444305

TOP1
DNA topoisomerase 1

2

2

High-throughput

0.789

High

492750

RL1
Large ribosomal subunit protein uL1

2

5

High-throughput

0.759

High

497105

DEAD
ATP-dependent RNA helicase DeaD

2

18

High-throughput

0.759

High

421121

PNP
Polyribonucleotide nucleotidyltransferase

3

6

High-throughput

0.669

High

638612

RL2
Large ribosomal subunit protein uL2

3

11

High-throughput

0.657

High

638610

RLUB
Ribosomal large subunit pseudouridine synthase B

2

4

High-throughput

0.640

High

638609

RLMN
Dual-specificity RNA methyltransferase RlmN

2

1

High-throughput

0.620

High

638605

RNE
Ribonuclease E

3

3

High-throughput

0.611

High

497993

YBCJ
Putative RNA-binding protein YbcJ

2

2

High-throughput

0.588

High

638613

RL24
Large ribosomal subunit protein uL24

2

1

High-throughput

0.588

High

473303

DNAJ
Chaperone protein DnaJ

1

5

High-throughput

0.561

High

497632

RLUC
Ribosomal large subunit pseudouridine synthase C

1

4

High-throughput

0.561

High

506262

EFTU1
Elongation factor Tu 1

2

8

High-throughput

0.558

High

494460

RS9
Small ribosomal subunit protein uS9

1

8

High-throughput

0.536

High

498955

DNAB
Replicative DNA helicase DnaB

1

1

High-throughput

0.536

High

638607

NIKE
Nickel import ATP-binding protein NikE

1

0

High-throughput

0.513

High

569567

SELB
Selenocysteine-specific elongation factor

1

9

High-throughput

0.512

High

493779

RS2
Small ribosomal subunit protein uS2

1

11

High-throughput

0.489

High

638606

FTSP
Cell division protein FtsP

1

1

High-throughput

0.489

High

638608

CBPA
Curved DNA-binding protein

1

4

High-throughput

0.489

High

638619

RLMKL
Ribosomal RNA large subunit methyltransferase K/L [Includes: 23S rRNA m2G2445 methyltransferase

1

1

High-throughput

0.489

High

493933

RS3
Small ribosomal subunit protein uS3

1

6

High-throughput

0.484

High

499930

RL23
Large ribosomal subunit protein uL23

1

1

High-throughput

0.484

High

501100

SPOT
Bifunctional

1

2

High-throughput

0.484

High

638614

RL4
Large ribosomal subunit protein uL4

1

3

High-throughput

0.484

High

638615

RL22
Large ribosomal subunit protein uL22

1

7

High-throughput

0.484

High

491652

KPRS
Ribose-phosphate pyrophosphokinase

1

1

High-throughput

0.479

High

492520

RL7
Large ribosomal subunit protein bL12

1

0

High-throughput

0.464

High

491506

IF3
Translation initiation factor IF-3 [Cleaved into: Translation initiation factor IF-3, N-terminally processed; Translation initiation factor IF-3S]

1

0

High-throughput

0.458

High

495019

TNAA
Tryptophanase

1

0

High-throughput

0.458

High

495579

TMAR
Pole-localizer protein TmaR

1

0

High-throughput

0.458

High

506327

EFTU2
Elongation factor Tu 2

1

8

High-throughput

0.457

High

498307

PCNB
Poly(A) polymerase I

1

1

Small-scale

0.445

High

491946

RPPH
RNA pyrophosphohydrolase

1

1

High-throughput

0.442

High

495441

TRMB
tRNA

1

1

High-throughput

0.442

High

638620

YNCE
Uncharacterized protein YncE

1

1

High-throughput

0.437

High

638618

YBJX
Uncharacterized protein YbjX

2

0

High-throughput

0.318

High

638617

YODC
Uncharacterized protein YodC

1

0

High-throughput

0.269

Low

492043

PLSB
Glycerol-3-phosphate acyltransferase

1

0

High-throughput

0.253

Low

638611

YJJU
Uncharacterized protein YjjU

1

0

High-throughput

0.249

Low

638616

LOLB
Outer-membrane lipoprotein LolB

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025