HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: PGAM1 (P18669)
Phosphoglycerate mutase 1 (EC 5.4.2.11) (EC 5.4.2.4) (BPG-dependent PGAM 1) (Phosphoglycerate mutase isozyme B) (PGAM-B)
Gene: PGAM1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	32812023, 35063084
Identification Methods	affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019901 - protein kinase binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 254
+	Mm
		498137 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		PGAM1_MOUSE (1-254): 5.34e-116: 334: 99.61
+	Hs
		241675 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		F262_HUMAN (1-253): 2.33e-60: 200: 19.37
+	Hs
		497118 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		F263_HUMAN (1-239): 1.29e-57: 193: 20.50
+	Hs
		430413 CEL_HUMAN (351-547): 2.38e-09: 62.7: 18.54		PMGE_HUMAN (1-254): 1.1e-102: 300: 53.52