HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: RBMS3 (Q6XE24)
RNA-binding motif, single-stranded-interacting protein 3
Gene: RBMS3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26269332
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0010629 - negative regulation of gene expression
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 437
+	Hs
		496957 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PABP4_HUMAN (52-230): 8.76e-40: 153: 22.87
+	Hs
		496179 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PABP1_HUMAN (52-230): 7.79e-37: 144: 25.00
+	Rn
		582032 TAU_RAT (1-758): 4.86e-75: 260: 71.47		PABP1_RAT (52-230): 4.23e-37: 145: 25.00
+	Rn
		94258 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		PABP1_RAT (52-230): 4.23e-37: 145: 25.00
+	Hs
		496937 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ELAV2_HUMAN (131-221): 1.61e-18: 88.3: 22.83
+	Mm
		498054 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		Q62029_MOUSE (52-228): 2.6e-36: 142: 24.73
+	Hs
		497082 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ELAV1_HUMAN (142-208): 1.09e-14: 76.8: 33.82
+	Hs
		497020 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ELAV3_HUMAN (142-230): 7.78e-14: 74.5: 25.56
+	Hs
		496346 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ELAV4_HUMAN (142-208): 2.05e-12: 70.3: 29.41
+	Mm
		498050 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		ELAV4_MOUSE (142-208): 2.06e-12: 70.3: 29.41
+	Hs
		516595 KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91		PABP1_HUMAN (52-230): 7.79e-37: 144: 25.00