HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: BD1L1 (Q8NFC6)
Biorientation of chromosomes in cell division protein 1-like 1
Gene: BOD1L1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	36634849, 26269332
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006974 - DNA damage response
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 3051
+	Hs
		1056897 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		BD1L1_HUMAN (50-3051): 0: 2178: 100.00
+	Hs
		152668 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		BD1L1_HUMAN (50-3051): 0: 2178: 100.00
+	Hs
		1243827 KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91		BD1L1_HUMAN (50-3051): 0: 2178: 100.00
+	Hs
		496438 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MYH9_HUMAN (569-1501): 3.76e-40: 167: 10.73
+	Hs
		64577 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MYH7B_HUMAN (20-983): 5.35e-31: 137: 8.30
+	Hs
		497051 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PLEC_HUMAN (275-1676): 2.39e-27: 125: 9.38
+	Hs
		496439 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MYH10_HUMAN (771-1629): 8.52e-24: 113: 11.04
+	Hs
		497209 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		WDR87_HUMAN (235-1099): 2.53e-22: 108: 15.83
+	Hs
		496228 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		DESP_HUMAN (205-1104): 1.48e-20: 102: 15.80
+	Hs
		497769 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MYH2_HUMAN (946-1735): 2.97e-19: 98.5: 8.79
+	Hs
		497371 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MY18A_HUMAN (545-1152): 4.98e-12: 74.5: 15.09
+	Rn
		582036 TAU_RAT (1-758): 4.86e-75: 260: 71.47		MYH10_RAT (771-1635): 1.83e-23: 112: 11.36
+	Rn
		94262 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		MYH10_RAT (771-1635): 1.83e-23: 112: 11.36
+	Hs
		503287 MTAP2_HUMAN (16-758): 2.28e-30: 131: 23.55		PLEC_HUMAN (275-1676): 2.39e-27: 125: 9.38
+	Dm
		54892 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		A1ZA72_DROME (96-1725): 3.38e-38: 161: 9.58
+	Dm
		1370292 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		Q9VTY8_DROME (197-1008): 2.56e-14: 82.2: 15.81
+	Dm
		116377 CPN_DROME (345-756): 7.29e-11: 67.8: 11.17		M9PI41_DROME (197-1008): 2.22e-14: 82.2: 15.81
+	Dm
		973540 CPN_DROME (345-756): 7.29e-11: 67.8: 11.17		Q9VTY8_DROME (197-1008): 2.56e-14: 82.2: 15.81