Protein: URB2
Nucleolar pre-ribosomal-associated protein 2 (Unhealthy ribosome biogenesis protein 2)

Gene: URB2
Organism: Saccharomyces cerevisiae S288C
Interactions: 107
UniProt ID: P47108

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0006364 - rRNA processing
GO:0016072 - rRNA metabolic process
GO:0042254 - ribosome biogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

811783

DBP6
ATP-dependent RNA helicase DBP6

7

1

Small-scale

0.742

High

710897

URB1
Nucleolar pre-ribosomal-associated protein 1

9

0

Small-scale

0.717

High

811798

RSA3
Ribosome assembly protein 3

6

0

Small-scale

0.706

High

811805

NOP8
60S ribosome subunit biogenesis protein NOP8

4

0

Small-scale

0.648

High

811816

NOP58
Nucleolar protein 58

3

1

High-throughput

0.640

High

811810

YTM1
Ribosome biogenesis protein YTM1

3

0

High-throughput

0.618

High

792490

UTP10
U3 small nucleolar RNA-associated protein 10

3

0

High-throughput

0.613

High

733138

DBP7
ATP-dependent RNA helicase DBP7

2

2

Small-scale

0.584

High

811815

NOP56
Nucleolar protein 56

2

1

High-throughput

0.584

High

634422

SPB1
27S pre-rRNA

2

0

High-throughput

0.569

High

755301

RPF1
Ribosome production factor 1

2

0

High-throughput

0.569

High

535039

RL3
Large ribosomal subunit protein uL3

2

0

High-throughput

0.559

High

748649

ENP1
Essential nuclear protein 1

2

0

High-throughput

0.559

High

754876

SSF1
Ribosome biogenesis protein SSF1

2

0

High-throughput

0.559

High

764199

NOC2
Nucleolar complex protein 2

2

0

High-throughput

0.559

High

811801

DBP9
ATP-dependent RNA helicase DBP9

2

0

Small-scale

0.559

High

511859

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.536

High

405222

RL17A
Large ribosomal subunit protein uL22A

2

1

Small-scale

0.533

High

810255

RL17B
Large ribosomal subunit protein uL22B

2

1

Small-scale

0.533

High

676176

XPO1
Exportin-1

1

0

High-throughput

0.513

High

811804

NOP6
Nucleolar protein 6

1

0

High-throughput

0.513

High

635132

YCQ6
Uncharacterized protein YCR016W

1

0

High-throughput

0.493

High

710185

NCBP1
Nuclear cap-binding protein complex subunit 1

1

0

High-throughput

0.493

High

731486

YRA2
RNA annealing protein YRA2

1

0

High-throughput

0.493

High

811789

IMA1
Importin subunit alpha

1

0

High-throughput

0.493

High

811800

IMB1
Importin subunit beta-1

1

0

High-throughput

0.493

High

811808

NCBP2
Nuclear cap-binding protein subunit 2

1

0

High-throughput

0.493

High

811811

YRA1
RNA annealing protein YRA1

1

0

High-throughput

0.493

High

635603

PWP2
Periodic tryptophan protein 2

1

1

High-throughput

0.479

High

638803

SPB4
ATP-dependent rRNA helicase SPB4

1

1

High-throughput

0.479

High

744207

MAK5
ATP-dependent RNA helicase MAK5

1

1

High-throughput

0.479

High

811782

YG5X
Putative methyltransferase YGR283C

1

1

High-throughput

0.479

High

811790

HAS1
ATP-dependent RNA helicase HAS1

1

1

High-throughput

0.479

High

811796

YM91
Putative methyltransferase YMR310C

1

1

High-throughput

0.479

High

811799

UTP21
U3 small nucleolar RNA-associated protein 21

1

2

High-throughput

0.479

High

811802

NOC4
Nucleolar complex protein 4

1

1

High-throughput

0.479

High

811812

MAK21
Ribosome biogenesis protein MAK21

1

1

High-throughput

0.479

High

811814

UTP12
U3 small nucleolar RNA-associated protein 12

1

1

High-throughput

0.479

High

339720

CDK1
Cyclin-dependent kinase 1

1

0

High-throughput

0.458

High

392493

H2A2
Histone H2A.2

1

0

High-throughput

0.458

High

405707

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.458

High

407161

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

498985

RL4A
Large ribosomal subunit protein uL4A

1

0

High-throughput

0.458

High

501229

MAK16
Protein MAK16

1

0

High-throughput

0.458

High

549431

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.458

High

640993

RL5
Large ribosomal subunit protein uL18

1

0

Small-scale

0.458

High

662657

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

704369

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.458

High

715947

UTP20
U3 small nucleolar RNA-associated protein 20

1

0

High-throughput

0.458

High

742029

NOP4
Nucleolar protein 4

1

0

High-throughput

0.458

High

754142

CIC1
Proteasome-interacting protein CIC1

1

0

High-throughput

0.458

High

776453

RLP7
Ribosome biogenesis protein RLP7

1

0

High-throughput

0.458

High

778812

NOP2
25S rRNA

1

0

Small-scale

0.458

High

811318

NOP9
Nucleolar protein 9

1

0

High-throughput

0.458

High

811776

URB2
Nucleolar pre-ribosomal-associated protein 2

1

0

High-throughput

0.458

High

811780

UTP22
U3 small nucleolar RNA-associated protein 22

1

0

High-throughput

0.458

High

811781

PESC
Pescadillo homolog

1

0

High-throughput

0.458

High

811784

NOG2
Nucleolar GTP-binding protein 2

1

0

High-throughput

0.458

High

811785

NOP13
Nucleolar protein 13

1

0

High-throughput

0.458

High

811786

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

811791

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.458

High

811792

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

811793

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.458

High

811794

UTP14
U3 small nucleolar RNA-associated protein 14

1

0

High-throughput

0.458

High

811795

ERB1
Ribosome biogenesis protein ERB1

1

0

High-throughput

0.458

High

811797

RRP5
rRNA biogenesis protein RRP5

1

0

High-throughput

0.458

High

811806

SGO1
Shugoshin

1

0

High-throughput

0.458

High

811809

BMS1
Ribosome biogenesis protein BMS1

1

0

High-throughput

0.458

High

811813

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

811817

RRP12
Ribosomal RNA-processing protein 12

1

0

High-throughput

0.458

High

811818

NOP14
Nucleolar complex protein 14

1

0

High-throughput

0.458

High

491700

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

494340

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

680835

HS104
Heat shock protein 104

1

1

High-throughput

0.445

High

695013

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

768823

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

564322

RL8A
Large ribosomal subunit protein eL8A

1

1

High-throughput

0.437

High

667218

RL8B
Large ribosomal subunit protein eL8B

1

1

High-throughput

0.437

High

811777

RL37A
Large ribosomal subunit protein eL37A

1

1

Small-scale

0.437

High

811778

RL37B
Large ribosomal subunit protein eL37B

1

1

Small-scale

0.437

High

560718

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.426

High

754517

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

705375

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.407

High

383230

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

471141

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

480759

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

524373

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

544016

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.249

Low

700502

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

700972

SMY2
Protein SMY2

1

0

High-throughput

0.249

Low

701495

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

706361

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

729996

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

750984

KPR2
Ribose-phosphate pyrophosphokinase 2

1

0

High-throughput

0.249

Low

752542

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

757999

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

Small-scale

0.249

Low

762353

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

765241

RS26B
Small ribosomal subunit protein eS26B

1

0

High-throughput

0.249

Low

775524

INP51
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase INP51

1

0

High-throughput

0.249

Low

811779

ART5
Arrestin-related trafficking adapter 5

1

0

High-throughput

0.249

Low

811787

NUM1
Nuclear migration protein NUM1

1

0

High-throughput

0.249

Low

811788

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

811807

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

424592

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.232

Low

810045

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low

811803

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024