HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: SEH1 (Q96EE3)
Nucleoporin SEH1 (GATOR2 complex protein SEH1) (Nup107-160 subcomplex subunit SEH1) (SEC13-like protein)
Gene: SEH1L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26269332
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 360
+	Hs
		496503 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		LIS1_HUMAN (272-360): 7.69e-17: 83: 16.85
+	Hs
		496657 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SEC13_HUMAN (216-346): 5.58e-17: 82.6: 18.80
+	Hs
		152663 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		WDR5B_HUMAN (78-360): 5.47e-51: 174: 17.31
+	Hs
		654026 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		FBXW7_HUMAN (3-246): 5.14e-41: 154: 14.34
+	Hs
		152678 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		FBXW7_HUMAN (3-246): 5.14e-41: 154: 14.34
+	Hs
		1281391 PRR36_HUMAN (1-607): 1.27e-15: 83.6: 10.11		FBXW7_HUMAN (3-246): 5.14e-41: 154: 14.34
+	Hs
		653951 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		WDR5_HUMAN (253-360): 5.88e-19: 88.4: 18.52
+	Hs
		1056932 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		SNR40_HUMAN (3-140): 3.35e-22: 98: 18.88
+	Hs
		152622 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		WDR5_HUMAN (253-360): 5.88e-19: 88.4: 18.52
+	Dm
		1370295 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		POC1_DROME (9-309): 3.76e-33: 128: 19.60
+	Mm
		903669 KMT2C_MOUSE (228-587): 6.06e-09: 61.9: 16.84		WDR5_MOUSE (253-360): 5.88e-19: 88.4: 18.52
+	Hs
		903374 KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91		WDR5_HUMAN (253-360): 5.88e-19: 88.4: 18.52