HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: WDR26 (Q9H7D7)
WD repeat-containing protein 26 (CUL4- and DDB1-associated WDR protein 2) (Myocardial ischemic preconditioning up-regulated protein 2)
Gene: WDR26

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32812023
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 758 Hs			1 661
+	Hs
		1056988 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		WDR26_HUMAN (28-661): 5.33e-158: 471: 100.00
+	Hs
		496503 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		LIS1_HUMAN (394-661): 1.17e-77: 255: 15.23
+	Hs
		497124 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SMU1_HUMAN (477-661): 1.05e-44: 169: 17.41
+	Hs
		496777 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		GBB2_HUMAN (462-661): 1.61e-37: 144: 12.20
+	Hs
		497176 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		A16L1_HUMAN (522-652): 1.81e-24: 110: 18.94
+	Hs
		497284 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		WDR17_HUMAN (373-610): 6.08e-13: 74.5: 16.54
+	Hs
		654026 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		FBXW7_HUMAN (314-594): 9.42e-60: 214: 14.53
+	Hs
		152678 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		FBXW7_HUMAN (314-594): 9.42e-60: 214: 14.53
+	Hs
		653951 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		WDR5_HUMAN (186-512): 3.62e-45: 165: 15.18
+	Hs
		1281391 PRR36_HUMAN (1-607): 1.27e-15: 83.6: 10.11		FBXW7_HUMAN (314-594): 9.42e-60: 214: 14.53
+	Hs
		152663 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		WDR5B_HUMAN (179-512): 1.46e-45: 166: 14.29
+	Hs
		152622 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		WDR5_HUMAN (186-512): 3.62e-45: 165: 15.18
+	Hs
		921574 SPEG_HUMAN (183-564): 6e-23: 107: 16.71		GBB2_HUMAN (462-661): 1.61e-37: 144: 12.20
+	Hs
		653993 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		A16L1_HUMAN (522-652): 1.81e-24: 110: 18.94
+	Mm
		903669 KMT2C_MOUSE (228-587): 6.06e-09: 61.9: 16.84		WDR5_MOUSE (186-512): 3.62e-45: 165: 15.18
+	Hs
		903374 KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91		WDR5_HUMAN (186-512): 3.62e-45: 165: 15.18
+	Hs
		1078285 SPEG_HUMAN (183-564): 6e-23: 107: 16.71		A16L1_HUMAN (522-652): 1.81e-24: 110: 18.94
+	Mm
		649213 MAP4_MOUSE (10-742): 3.04e-29: 127: 18.63		A16L1_MOUSE (356-473): 6.39e-15: 80.1: 19.67
+	Hs
		1056932 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		SNR40_HUMAN (17-381): 1.88e-13: 74.4: 13.39
+	Mm
		1207691 TARA_MOUSE (3-751): 2.63e-09: 63.2: 8.51		A16L1_MOUSE (356-473): 6.39e-15: 80.1: 19.67