HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: BCLF1 (Q9NYF8)
Bcl-2-associated transcription factor 1 (Btf) (BCLAF1 and THRAP3 family member 1)
Gene: BCLAF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0006974 - DNA damage response and 1 others more... GO:0016607 - nuclear speck
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 920
+	Hs
		497848 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TR150_HUMAN (46-920): 4.85e-76: 269: 33.00
+	Hs
		496871 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ANK2_HUMAN (84-795): 6.58e-49: 191: 11.52
+	Hs
		1057033 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		TR150_HUMAN (46-920): 4.85e-76: 269: 33.00
+	Hs
		497357 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TITIN_HUMAN (94-778): 5.89e-11: 69.2: 8.45
+	Rn
		94083 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		F1LRZ7_RAT (215-853): 4.21e-14: 78.8: 11.49
+	Rn
		562615 TAU_RAT (1-758): 4.86e-75: 260: 71.47		NFH_RAT (369-893): 1.94e-09: 63.8: 13.26
+	Dm
		113976 M9PB30_DROME (69-755): 2.38e-24: 112: 8.39		M9PB30_DROME (101-799): 1.06e-17: 91.2: 9.32
+	Hs
		1056937 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		CHAP1_HUMAN (114-643): 1.32e-09: 64.2: 11.09
+	Ce
		136802 UNC89_CAEEL (4-459): 4.47e-21: 101: 12.37		UNC22_CAEEL (120-782): 2.08e-10: 67.3: 13.65
+	Dm
		54892 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		A1ZA72_DROME (106-772): 4.43e-09: 62.7: 10.70
+	Mm
		1351630 PCLO_MOUSE (6-742): 3.27e-11: 69.3: 9.66		PCLO_MOUSE (94-904): 3.98e-10: 66.5: 9.22