HitPredict

Interactor 1: KAP0 (P10644)
cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue-specific extinguisher 1) (TSE1)
Gene: PRKAR1A

Interactor 2: AKAP4 (Q5JQC9)
A-kinase anchor protein 4 (AKAP-4) (A-kinase anchor protein 82 kDa) (AKAP 82) (hAKAP82) (Major sperm fibrous sheath protein) (HI) (Protein kinase A-anchoring protein 4) (PRKA4)
Gene: AKAP4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.786

Property	Details
Experiments	12606363, 9852104
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	RII_binding_1~RIIa
Common GO terms	GO:0005737 - cytoplasm GO:0005952 - cAMP-dependent protein kinase complex
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 381 Hs			1 854
+	Hs
		533840 KAP2_HUMAN (233-379): 1.21e-17: 85.5: 26.53		AKAP4_HUMAN (1-854): 0: 1193: 100.00
+	Hs
		279998 KAP0_HUMAN (1-381): 1.4e-139: 404: 100.00		AKAP3_HUMAN (10-854): 0: 861: 31.48
+	Bt
		285138 KAP2_BOVIN (233-379): 1.96e-17: 85.1: 26.53		AKAP3_BOVIN (10-854): 0: 914: 32.99
+	Hs
		279999 KAP2_HUMAN (233-379): 1.21e-17: 85.5: 26.53		AKAP3_HUMAN (10-854): 0: 861: 31.48
+	Mm
		522356 KAP1_MOUSE (1-381): 2.29e-142: 410: 81.37		SPKAP_MOUSE (481-852): 3.43e-98: 338: 17.42
+	Hs
		498373 KAP0_HUMAN (1-381): 1.4e-139: 404: 100.00		AKA11_HUMAN (491-853): 7.66e-81: 287: 14.02
+	Hs
		679325 KAP1_HUMAN (1-381): 1.35e-138: 401: 81.37		AKA11_HUMAN (491-853): 7.66e-81: 287: 14.02
+	Hs
		679410 KAP3_HUMAN (10-253): 4.9e-21: 95.9: 18.21		AKA11_HUMAN (491-853): 7.66e-81: 287: 14.02
+	Hs
		533884 KAP2_HUMAN (233-379): 1.21e-17: 85.5: 26.53		AKA11_HUMAN (491-853): 7.66e-81: 287: 14.02
+	Rn
		519445 KAP2_RAT (233-379): 4.01e-17: 83.9: 26.53		AKA11_RAT (491-782): 5.87e-60: 223: 12.33