HitPredict

Interactor 1: GLRX4 (O74790)
Monothiol glutaredoxin-4
Gene: grx4

Interactor 2: UVI31 (Q12238)
UV-induced protein uvi31 (BolA-like protein 1)
Gene: UVI31

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	26771498
Identification Methods	two hybrid, protein complementation assay
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	BolA~Glutaredoxin
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 244 Sp			1 102
+	Sp
		153749 GLRX4_SCHPO (1-244): 8.76e-67: 208: 100.00		YETB_SCHPO (9-101): 5.88e-23: 86.1: 23.66
+	Hs
		300257 GLRX3_HUMAN (7-243): 6.51e-56: 183: 35.44		BOLA1_HUMAN (12-101): 2.53e-29: 103: 38.89
+	Sc
		1044196 GLRX3_YEAST (2-235): 1.66e-56: 182: 43.04		BOL1_YEAST (1-101): 1.26e-26: 96.1: 43.93
+	Hs
		300237 GLRX3_HUMAN (7-243): 6.51e-56: 183: 35.44		BOLA2_HUMAN (8-102): 2.92e-23: 86.8: 21.05
+	Sc
		916994 GLRX3_YEAST (2-235): 1.66e-56: 182: 43.04		BOL2_YEAST (3-102): 1.23e-21: 83.8: 20.79
+	Sc
		744235 GLRX4_YEAST (2-235): 1.38e-51: 169: 40.93		BOL1_YEAST (1-101): 1.26e-26: 96.1: 43.93
+	Sc
		813884 GLRX3_YEAST (2-235): 1.66e-56: 182: 43.04		BOL3_YEAST (3-97): 1.33e-20: 81.1: 21.21
+	Sc
		744226 GLRX4_YEAST (2-235): 1.38e-51: 169: 40.93		BOL2_YEAST (3-102): 1.23e-21: 83.8: 20.79
+	Hs
		300156 GLRX3_HUMAN (7-243): 6.51e-56: 183: 35.44		BOLA3_HUMAN (4-95): 2.8e-15: 67.2: 23.40
+	Sc
		744224 GLRX4_YEAST (2-235): 1.38e-51: 169: 40.93		BOL3_YEAST (3-97): 1.33e-20: 81.1: 21.21
+	Hs
		1286667 GLRX5_HUMAN (148-243): 1.7e-42: 143: 49.49		BOLA1_HUMAN (12-101): 2.53e-29: 103: 38.89
+	At
		1285025 GRS16_ARATH (47-243): 1.17e-35: 129: 27.81		SUFE1_ARATH (10-101): 5.54e-31: 113: 47.31
+	At
		1228146 GRS16_ARATH (47-243): 1.17e-35: 129: 27.81		BOLA1_ARATH (7-100): 5.54e-31: 108: 46.81
+	Dm
		55144 Q9VJZ6_DROME (2-243): 8.39e-46: 153: 30.45		A1Z933_DROME (14-101): 2.5e-21: 82.2: 27.27
+	Ec
		498291 GLRX4_ECOLI (148-244): 4.19e-39: 133: 38.14		BOLA_ECOLI (9-101): 3.78e-28: 99: 30.11
+	Sc
		1038589 GLRX5_YEAST (142-244): 5.23e-39: 134: 42.45		BOL1_YEAST (1-101): 1.26e-26: 96.1: 43.93
+	At
		1300995 GRS16_ARATH (47-243): 1.17e-35: 129: 27.81		BOLA2_ARATH (9-101): 1.99e-25: 92.6: 24.73
+	Sc
		813883 GLRX5_YEAST (142-244): 5.23e-39: 134: 42.45		BOL3_YEAST (3-97): 1.33e-20: 81.1: 21.21
+	Hs
		1200389 GLRX5_HUMAN (148-243): 1.7e-42: 143: 49.49		BOLA3_HUMAN (4-95): 2.8e-15: 67.2: 23.40
+	Ec
		497300 GLRX4_ECOLI (148-244): 4.19e-39: 133: 38.14		IBAG_ECOLI (49-102): 1.17e-15: 67.6: 36.36