Protein: GLRX5
Glutaredoxin-related protein 5, mitochondrial (Monothiol glutaredoxin-5)

Gene: GLRX5
Organism: Homo sapiens
Interactions: 36
UniProt ID: Q86SX6

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006879 - intracellular iron ion homeostasis
GO:0016226 - iron-sulfur cluster assembly
GO:0030097 - hemopoiesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1200389

BOLA3
BolA-like protein 3

6

20

Small-scale

0.953

High

1286667

BOLA1
BolA-like protein 1

4

20

Small-scale

0.899

High

1286655

HSC20
Iron-sulfur cluster co-chaperone protein HscB

2

0

Small-scale

0.602

High

1162402

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

0

High-throughput

0.559

High

1234437

MRM1
rRNA methyltransferase 1, mitochondrial

2

0

High-throughput

0.547

High

1286663

TR61B
tRNA

2

0

High-throughput

0.547

High

422454

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

532723

CH60
60 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.479

High

1090452

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

7

High-throughput

0.479

High

1286657

CHC10
Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial

1

1

High-throughput

0.479

High

1286660

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.479

High

1286661

COQ7
NADPH-dependent 3-demethoxyubiquinone 3-hydroxylase, mitochondrial

1

1

High-throughput

0.479

High

1286662

DHRS4
Dehydrogenase/reductase SDR family member 4

1

2

High-throughput

0.479

High

1286669

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

1

High-throughput

0.479

High

143865

NDKM
Nucleoside diphosphate kinase, mitochondrial

1

0

High-throughput

0.458

High

275052

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.458

High

283898

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

1

0

High-throughput

0.458

High

505442

CISD3
CDGSH iron-sulfur domain-containing protein 3, mitochondrial

1

0

High-throughput

0.458

High

680411

ATPA
ATP synthase F(1) complex subunit alpha, mitochondrial

1

0

High-throughput

0.458

High

822739

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.458

High

1142588

PDK1
[Pyruvate dehydrogenase

1

0

High-throughput

0.458

High

1218330

SDHF4
Succinate dehydrogenase assembly factor 4, mitochondrial

1

0

High-throughput

0.458

High

1286656

SPT20
Spermatogenesis-associated protein 20

1

0

High-throughput

0.458

High

1286664

NMES1
Normal mucosa of esophagus-specific gene 1 protein

1

0

High-throughput

0.458

High

1286665

ZFYV1
Zinc finger FYVE domain-containing protein 1

1

0

Small-scale

0.458

High

1286666

SDHF3
Succinate dehydrogenase assembly factor 3, mitochondrial

1

0

High-throughput

0.458

High

1286654

ISCA2
Iron-sulfur cluster assembly 2 homolog, mitochondrial

1

3

High-throughput

0.445

High

349141

LATS1
Serine/threonine-protein kinase LATS1

1

1

High-throughput

0.437

High

777618

HMGCL
Hydroxymethylglutaryl-CoA lyase, mitochondrial

1

0

High-throughput

0.426

High

1286658

SYMM
Methionine--tRNA ligase, mitochondrial

1

0

High-throughput

0.426

High

1286659

MCEE
Methylmalonyl-CoA epimerase, mitochondrial

1

0

High-throughput

0.426

High

1121439

KEAP1
Kelch-like ECH-associated protein 1

1

0

High-throughput

0.282

High

380084

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.249

Low

459652

PROF1
Profilin-1

1

0

High-throughput

0.249

Low

879231

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

1286668

TLN1
Talin-1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025