Interactor 1: IMDH (P0ADG7)
Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPD) (IMPDH) (EC 1.1.1.205)
Gene: guaB

Interactor 2: IMDH (P0ADG7)
Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPD) (IMPDH) (EC 1.1.1.205)
Gene: guaB

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.757

The method score is based on:

Property Details
Experiments 36748301, 16858726
Identification Methods two hybrid, blue native page
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CBS~CBS, IMPDH~IMPDH
Common GO terms GO:0003697 - single-stranded DNA binding
GO:0003938 - IMP dehydrogenase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006177 - GMP biosynthetic process
and 7 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 488
Ec

1 488
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Hs
+ Hs
+ Hs
+ Cj
+ Dm
+ Sp
+ Pa
+ Sc
+ Sc
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025