Interactor 1: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5
Interactor 2: MANF (P55145)
Mesencephalic astrocyte-derived neurotrophic factor (Arginine-rich protein) (Protein ARMET)
Gene: MANF
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.44 | 0.90 | 0.631 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 30021884 |
| Identification Methods | proximity labelling technology, cross-linking study |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | ARMET_C~HSP70 |
| Common GO terms | GO:0005634 - nucleus GO:0005783 - endoplasmic reticulum GO:0005788 - endoplasmic reticulum lumen GO:0005829 - cytosol |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
