HitPredict

Interactor 1: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Interactor 2: ID2 (Q02363)
DNA-binding protein inhibitor ID-2 (Class B basic helix-loop-helix protein 26) (bHLHb26) (Inhibitor of DNA binding 2) (Inhibitor of differentiation 2)
Gene: ID2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

Property	Details
Experiments	26735018, 21988832
Identification Methods	affinity chromatography technology, two hybrid, two hybrid array
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0032991 - protein-containing complex
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 654 Hs			1 134
+	Hs
		713947 HS71L_HUMAN (24-647): 0: 922: 63.16		ID2_HUMAN (1-134): 1.82e-70: 209: 100.00
+	Hs
		503925 HSP7C_HUMAN (26-637): 0: 916: 66.02		ID2_HUMAN (1-134): 1.82e-70: 209: 100.00