HitPredict

Interactor 1: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Interactor 2: PRDX1 (Q06830)
Peroxiredoxin-1 (EC 1.11.1.24) (Natural killer cell-enhancing factor A) (NKEF-A) (Proliferation-associated gene protein) (PAG) (Thioredoxin peroxidase 2) (Thioredoxin-dependent peroxide reductase 2) (Thioredoxin-dependent peroxiredoxin 1)
Gene: PRDX1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36042349
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0042470 - melanosome GO:0045296 - cadherin binding and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 654 Hs			1 199
+	Hs
		503953 HSP7C_HUMAN (26-637): 0: 916: 66.02		PRDX1_HUMAN (1-199): 2.21e-105: 302: 100.00
+	Hs
		503536 HSP7C_HUMAN (26-637): 0: 916: 66.02		PRDX2_HUMAN (1-198): 2.38e-103: 297: 77.78
+	Hs
		504009 HSP7C_HUMAN (26-637): 0: 916: 66.02		PRDX4_HUMAN (4-197): 4.03e-95: 279: 69.59
+	Hs
		502045 BIP_HUMAN (19-654): 0: 914: 100.00		PRDX4_HUMAN (4-197): 4.03e-95: 279: 69.59
+	Hs
		503505 HSP7C_HUMAN (26-637): 0: 916: 66.02		PRDX6_HUMAN (4-197): 5.84e-67: 206: 28.50