HitPredict

Interactor 1: H2A1 (P0C0S8)
Histone H2A type 1 (H2A.1) (Histone H2A/ptl)
Gene: H2AC11

Interactor 2: SP16H (Q9Y5B9)
FACT complex subunit SPT16 (Chromatin-specific transcription elongation factor 140 kDa subunit) (FACT 140 kDa subunit) (FACTp140) (Facilitates chromatin transcription complex subunit SPT16) (hSPT16)
Gene: SUPT16H

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.776

Property	Details
Experiments	33961781, 24463511
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~Rttp106-like_middle, Histone_H2A_C~Rttp106-like_middle
Common GO terms	GO:0005634 - nucleus
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 130 Hs			1 1047
+	Hs
		1232747 H2A2A_HUMAN (1-130): 8.46e-67: 199: 98.46		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		1272828 H2A3_HUMAN (1-130): 1.16e-66: 199: 97.69		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		419288 H2A1B_HUMAN (1-130): 1.37e-66: 199: 98.46		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		1162936 H2A2C_HUMAN (1-128): 4.58e-64: 192: 95.31		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		1413578 H2AJ_HUMAN (1-128): 4.53e-64: 192: 94.53		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		591904 H2AX_HUMAN (1-130): 6.66e-63: 190: 88.81		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Mm
		694448 H2AX_MOUSE (1-129): 1.62e-62: 189: 90.70		SP16H_MOUSE (1-1047): 0: 1332: 98.66
+	Sc
		419388 H2A1_YEAST (16-127): 4.06e-53: 165: 81.25		SPT16_YEAST (3-1008): 0: 938: 33.49
+	Sc
		419657 H2A2_YEAST (16-127): 4.06e-53: 165: 81.25		SPT16_YEAST (3-1008): 0: 938: 33.49