Protein: SYNEM
Synemin (Desmuslin)

Gene: SYNEM, SYNM
Organism: Homo sapiens
Interactions: 61
UniProt ID: O15061

Gene Ontology (top 5):
GO:0005200 - structural constituent of cytoskeleton
GO:0005882 - intermediate filament
GO:0005912 - adherens junction
GO:0008307 - structural constituent of muscle
GO:0017166 - vinculin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

166140

SYNCI
Syncoilin

2

20

High-throughput

0.811

High

166100

DESM
Desmin

2

20

Small-scale

0.799

High

166108

NEST
Nestin

1

20

High-throughput

0.691

High

166145

DNJB4
DnaJ homolog subfamily B member 4

4

3

High-throughput

0.633

High

166094

K2C8
Keratin, type II cytoskeletal 8

1

20

High-throughput

0.618

High

166095

VIME
Vimentin

1

20

High-throughput

0.618

High

166096

K1C19
Keratin, type I cytoskeletal 19

1

19

High-throughput

0.618

High

166099

GFAP
Glial fibrillary acidic protein

1

20

High-throughput

0.618

High

166107

PERI
Peripherin

1

20

High-throughput

0.618

High

166132

CT55
Cancer/testis antigen 55

3

4

High-throughput

0.609

High

166109

AMPH
Amphiphysin

3

7

Small-scale

0.585

High

166125

CP135
Centrosomal protein of 135 kDa

3

20

High-throughput

0.578

High

166147

DTNA
Dystrobrevin alpha

1

10

Small-scale

0.573

High

166112

GRB2
Growth factor receptor-bound protein 2

2

20

Small-scale

0.533

High

166093

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

13

High-throughput

0.526

High

166102

ERBB3
Receptor tyrosine-protein kinase erbB-3

2

17

High-throughput

0.526

High

166123

ERBB4
Receptor tyrosine-protein kinase erbB-4

2

16

High-throughput

0.526

High

166133

TITIN
Titin

1

20

Small-scale

0.506

High

166111

PKNX1
Homeobox protein PKNOX1

1

1

High-throughput

0.494

High

166101

CSK22
Casein kinase II subunit alpha'

1

1

High-throughput

0.489

High

166119

CUL4A
Cullin-4A

1

20

High-throughput

0.489

High

166129

CSN6
COP9 signalosome complex subunit 6

1

11

High-throughput

0.489

High

166124

ZYX
Zyxin

1

11

High-throughput

0.479

High

166120

FLNC
Filamin-C

1

11

Small-scale

0.457

High

166143

DISC1
Disrupted in schizophrenia 1 protein

1

3

Small-scale

0.457

High

166088

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

15

High-throughput

0.437

High

166090

TRI37
E3 ubiquitin-protein ligase TRIM37

1

20

High-throughput

0.437

High

166092

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.437

High

166097

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

13

Small-scale

0.437

High

166103

CBL
E3 ubiquitin-protein ligase CBL

1

16

Small-scale

0.437

High

166104

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

20

Small-scale

0.437

High

166105

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

1

Small-scale

0.437

High

166110

EMD
Emerin

1

1

High-throughput

0.437

High

166113

ARF5
ADP-ribosylation factor 5

1

5

High-throughput

0.437

High

166114

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

12

Small-scale

0.437

High

166115

EP300
Histone acetyltransferase p300

1

4

High-throughput

0.437

High

166116

FOXO1
Forkhead box protein O1

1

5

High-throughput

0.437

High

166121

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

2

High-throughput

0.437

High

166122

KIF14
Kinesin-like protein KIF14

1

20

High-throughput

0.437

High

166126

RNF43
E3 ubiquitin-protein ligase RNF43

1

18

High-throughput

0.437

High

166127

SYNE3
Nesprin-3

1

16

High-throughput

0.437

High

166128

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

166130

SLN11
Schlafen family member 11

1

1

High-throughput

0.437

High

166131

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

11

High-throughput

0.437

High

166135

DNJC1
DnaJ homolog subfamily C member 1

1

3

High-throughput

0.437

High

166137

SH3G2
Endophilin-A1

1

20

Small-scale

0.437

High

166138

LZTS2
Leucine zipper putative tumor suppressor 2

1

20

High-throughput

0.437

High

166139

PACN1
Protein kinase C and casein kinase substrate in neurons protein 1

1

6

Small-scale

0.437

High

166141

TNR6C
Trinucleotide repeat-containing gene 6C protein

1

15

High-throughput

0.437

High

166142

ANLN
Anillin

1

18

High-throughput

0.437

High

166144

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

2

High-throughput

0.437

High

166089

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

5

High-throughput

0.407

High

166098

CFTR
Cystic fibrosis transmembrane conductance regulator

1

20

High-throughput

0.407

High

166106

BMI1
Polycomb complex protein BMI-1

1

20

High-throughput

0.407

High

166117

CTBP1
C-terminal-binding protein 1

1

11

High-throughput

0.407

High

166136

ZBT18
Zinc finger and BTB domain-containing protein 18

1

11

High-throughput

0.407

High

166146

ITM2B
Integral membrane protein 2B

1

10

High-throughput

0.407

High

166091

CEP43
Centrosomal protein 43

1

0

High-throughput

0.279

Low

166134

SKA1
Spindle and kinetochore-associated protein 1

1

0

High-throughput

0.279

Low

166087

GRRE1
Granule associated Rac and RHOG effector protein 1

1

0

High-throughput

0.249

Low

166118

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024