HitPredict

Interactor 1: GTR1 (P11166)
Solute carrier family 2, facilitated glucose transporter member 1 (Glucose transporter type 1, erythrocyte/brain) (GLUT-1) (HepG2 glucose transporter)
Gene: SLC2A1

Interactor 2: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane GO:0030496 - midbody and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 492 Hs			1 191
+	Hs
		505332 GTR1_HUMAN (1-492): 6.2e-110: 336: 100.00		RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94
+	Hs
		505478 GTR1_HUMAN (1-492): 6.2e-110: 336: 100.00		RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17
+	Hs
		505385 GTR1_HUMAN (1-492): 6.2e-110: 336: 100.00		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		505390 GTR1_HUMAN (1-492): 6.2e-110: 336: 100.00		RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73
+	Hs
		505379 GTR1_HUMAN (1-492): 6.2e-110: 336: 100.00		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Hs
		505329 GTR1_HUMAN (1-492): 6.2e-110: 336: 100.00		RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75
+	Hs
		436134 GTR1_HUMAN (1-492): 6.2e-110: 336: 100.00		RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41
+	Hs
		505376 GTR1_HUMAN (1-492): 6.2e-110: 336: 100.00		RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32
+	Hs
		1254725 GTR14_HUMAN (1-468): 2.32e-101: 315: 64.74		RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17
+	Hs
		925456 GTR14_HUMAN (1-468): 2.32e-101: 315: 64.74		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		505429 GTR1_HUMAN (1-492): 6.2e-110: 336: 100.00		RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82
+	Hs
		951178 GTR14_HUMAN (1-468): 2.32e-101: 315: 64.74		RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73
+	Hs
		900720 GTR14_HUMAN (1-468): 2.32e-101: 315: 64.74		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Hs
		545515 GTR14_HUMAN (1-468): 2.32e-101: 315: 64.74		RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75
+	Rn
		583084 GLUT4_RAT (2-491): 2.16e-95: 299: 65.05		RAC1_RAT (1-191): 1.75e-84: 249: 70.31
+	Rn
		582806 GLUT4_RAT (2-491): 2.16e-95: 299: 65.05		RHOA_RAT (5-191): 9.99e-82: 242: 53.48
+	Rn
		582912 GLUT4_RAT (2-491): 2.16e-95: 299: 65.05		Q32PX6_RAT (1-191): 7.59e-82: 242: 60.73