HitPredict

Interactor 1: UBB (P0CG47)
Polyubiquitin-B [Cleaved into: Ubiquitin]
Gene: UBB

Interactor 2: FAF2 (Q96CS3)
FAS-associated factor 2 (UBX domain-containing protein 3B) (UBX domain-containing protein 8)
Gene: FAF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.691

Property	Details
Experiments	26186194, 28514442, 33961781, 18775313
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 229 Hs			1 445
+	Hs
		508411 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		FAF2_HUMAN (1-445): 1.33e-143: 419: 100.00
+	Hs
		320614 UBB_HUMAN (1-229): 2.65e-99: 289: 100.00		UBXN7_HUMAN (1-441): 1.1e-116: 352: 16.34
+	Hs
		320615 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		UBXN7_HUMAN (1-441): 1.1e-116: 352: 16.34
+	Mm
		509048 UBC_MOUSE (1-181): 8.42e-63: 209: 96.13		FAF2_MOUSE (1-445): 8.51e-142: 414: 97.75
+	Hs
		507428 UBB_HUMAN (1-229): 2.65e-99: 289: 100.00		FAF1_HUMAN (112-440): 5.65e-83: 269: 24.79
+	Hs
		508835 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		FAF1_HUMAN (112-440): 5.65e-83: 269: 24.79
+	Mm
		509111 UBC_MOUSE (1-181): 8.42e-63: 209: 96.13		UBXN7_MOUSE (1-441): 4.38e-110: 334: 16.57
+	Sc
		509736 UBI4P_YEAST (1-228): 3.4e-91: 274: 96.05		UBX5_YEAST (14-445): 5.59e-80: 257: 11.89
+	Sc
		509710 UBI4P_YEAST (1-228): 3.4e-91: 274: 96.05		UBX2_YEAST (9-430): 9.08e-66: 222: 16.38
+	Mm
		508990 UBC_MOUSE (1-181): 8.42e-63: 209: 96.13		FAF1_MOUSE (112-440): 1.59e-81: 265: 25.07
+	Rn
		1224496 UBC_RAT (1-181): 3.75e-62: 209: 96.13		FAF1_RAT (112-439): 2.89e-78: 257: 24.57
+	Hs
		507861 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		UBXN1_HUMAN (295-439): 7.97e-19: 88.4: 16.36
+	Mm
		509226 UBC_MOUSE (1-181): 8.42e-63: 209: 96.13		UBXN1_MOUSE (256-439): 8.81e-21: 94.1: 14.63