Protein: UBX2
UBX domain-containing protein 2 (Secretion lowering protein 1)

Gene: UBX2
Organism: Saccharomyces cerevisiae S288C
Interactions: 54
UniProt ID: Q04228

Gene Ontology (top 5):
GO:0000836 - Hrd1p ubiquitin ligase complex
GO:0000837 - Doa10p ubiquitin ligase complex
GO:0000839 - Hrd1p ubiquitin ligase ERAD-L complex
GO:0005741 - mitochondrial outer membrane
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1046144

UBX2
UBX domain-containing protein 2

3

0

High-throughput

0.805

High

680036

CDC48
Cell division control protein 48

17

0

Small-scale

0.731

High

1046149

HRD1
ERAD-associated E3 ubiquitin-protein ligase HRD1

8

0

Small-scale

0.720

High

509710

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

3

0

Small-scale

0.715

High

916744

UFD1
Ubiquitin fusion degradation protein 1

7

0

Small-scale

0.714

High

754448

NPL4
Nuclear protein localization protein 4

6

0

Small-scale

0.699

High

822280

DOA10
ERAD-associated E3 ubiquitin-protein ligase DOA10

5

0

Small-scale

0.690

High

797816

DER1
Degradation in the endoplasmic reticulum protein 1

3

0

Small-scale

0.634

High

1046146

HRD3
ERAD-associated E3 ubiquitin-protein ligase component HRD3

3

0

Small-scale

0.606

High

1046152

DFM1
DER1-like family member protein 1

2

1

Small-scale

0.601

High

1043818

USA1
U1 SNP1-associating protein 1

2

0

Small-scale

0.585

High

1046153

OS9
Protein OS-9 homolog

2

0

Small-scale

0.576

High

763195

TOM20
Mitochondrial import receptor subunit TOM20

2

0

Small-scale

0.559

High

779965

DOA1
Protein DOA1

2

0

Small-scale

0.559

High

797585

FZO1
Mitofusin FZO1

2

0

Small-scale

0.559

High

881435

TOM22
Mitochondrial import receptor subunit TOM22

2

0

Small-scale

0.559

High

1046145

VMS1
tRNA endonuclease VMS1

2

0

Small-scale

0.559

High

525064

HSP71
Heat shock protein SSA1

2

0

High-throughput

0.547

High

546176

SSB1
Ribosome-associated molecular chaperone SSB1

2

0

High-throughput

0.547

High

554446

HMDH2
3-hydroxy-3-methylglutaryl-coenzyme A reductase 2

1

0

Small-scale

0.513

High

580023

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.479

High

359349

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

0

High-throughput

0.458

High

574926

SAM35
Sorting assembly machinery 35 kDa subunit

1

0

Small-scale

0.458

High

598485

SEN2
tRNA-splicing endonuclease subunit SEN2

1

0

Small-scale

0.458

High

661826

TOM40
Mitochondrial import receptor subunit TOM40

1

0

Small-scale

0.458

High

677659

LDB16
Protein LDB16

1

0

Small-scale

0.458

High

757865

PTH2
Peptidyl-tRNA hydrolase 2

1

0

Small-scale

0.458

High

764200

SPT23
Protein SPT23

1

0

Small-scale

0.458

High

780796

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

1

0

High-throughput

0.458

High

815564

RSP5
E3 ubiquitin-protein ligase RSP5

1

0

Small-scale

0.458

High

924460

CUZ1
CDC48-associated ubiquitin-like/zinc finger protein 1

1

0

Small-scale

0.458

High

932797

UFD2
E4 ubiquitin-protein ligase UFD2

1

0

Small-scale

0.458

High

1030541

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

0

Small-scale

0.458

High

1046147

SEI1
Seipin

1

0

Small-scale

0.458

High

1046150

DGAT2
Diacylglycerol O-acyltransferase 1

1

0

Small-scale

0.458

High

918398

FMP48
Probable serine/threonine-protein kinase FMP48

1

1

High-throughput

0.457

High

393289

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.445

High

366061

CBPY
Carboxypeptidase Y

1

0

Small-scale

0.426

High

676325

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.426

High

1035074

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

Small-scale

0.426

High

571852

SNA3
Protein SNA3

1

0

High-throughput

0.282

High

1046151

ENG2
Glucan endo-1,3-beta-D-glucosidase 2

1

0

High-throughput

0.282

High

437956

KAPC
cAMP-dependent protein kinase type 3

1

0

High-throughput

0.261

Low

403650

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

High-throughput

0.249

Low

444619

DED1
ATP-dependent RNA helicase DED1

1

0

High-throughput

0.249

Low

531880

RL4A
Large ribosomal subunit protein uL4A

1

0

High-throughput

0.249

Low

570302

RS17B
Small ribosomal subunit protein eS17B

1

0

High-throughput

0.249

Low

603104

EST1
Telomere elongation protein EST1

1

0

High-throughput

0.249

Low

752699

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.249

Low

1026825

CDC14
Tyrosine-protein phosphatase CDC14

1

0

Small-scale

0.249

Low

1043565

ESC1
Silent chromatin protein ESC1

1

0

High-throughput

0.249

Low

1046148

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

807138

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025