Protein: HDAC6
Protein deacetylase HDAC6 (EC 3.5.1.-) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) (mHDA2)

Gene: HDAC6
Organism: Mus musculus
Interactions: 29
UniProt ID: Q9Z2V5

Gene Ontology (top 5):
GO:0000118 - histone deacetylase complex
GO:0000209 - protein polyubiquitination
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001222 - transcription corepressor binding
GO:0001975 - response to amphetamine

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

509339

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

2

13

Small-scale

0.778

High

547289

HS90B
Heat shock protein HSP 90-beta

3

17

Small-scale

0.640

High

682004

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

20

Small-scale

0.618

High

1362261

HDA11
Histone deacetylase 11

1

20

Small-scale

0.618

High

1490187

PRKN
E3 ubiquitin-protein ligase parkin

1

16

Small-scale

0.618

High

997275

TBA1A
Tubulin alpha-1A chain

2

14

Small-scale

0.595

High

1033508

TERA
Transitional endoplasmic reticulum ATPase

2

6

Small-scale

0.584

High

1296927

Q8BLD3
Coiled-coil domain-containing 141

1

14

Small-scale

0.523

High

237194

SEPT7
Septin-7

1

4

Small-scale

0.515

High

693481

PLAP
Phospholipase A-2-activating protein

1

14

Small-scale

0.515

High

728547

AKT1
RAC-alpha serine/threonine-protein kinase

1

7

Small-scale

0.515

High

98241

CC141
Coiled-coil domain-containing protein 141

1

20

Small-scale

0.479

High

530953

TAU
Microtubule-associated protein tau

1

12

Small-scale

0.479

High

648086

MYD88
Myeloid differentiation primary response protein MyD88

1

1

Small-scale

0.479

High

1046002

TF65
Transcription factor p65

1

20

Small-scale

0.479

High

1189854

DDB1
DNA damage-binding protein 1

1

11

Small-scale

0.479

High

1223386

MYH10
Myosin-10

1

13

Small-scale

0.479

High

1281918

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

Small-scale

0.479

High

1298648

KAT5
Histone acetyltransferase KAT5

1

5

Small-scale

0.479

High

1408897

HDAC9
Histone deacetylase 9

1

18

Small-scale

0.479

High

1021192

NXN
Nucleoredoxin

1

0

Small-scale

0.458

High

1189304

STING
Stimulator of interferon genes protein

1

0

High-throughput

0.458

High

1423584

FBX32
F-box only protein 32

1

0

Small-scale

0.458

High

555585

NR4A1
Nuclear receptor subfamily 4 group A member 1

1

20

Small-scale

0.445

High

1298549

FTM
Protein fantom

1

20

High-throughput

0.445

High

97676

E9PV60
WD repeat and FYVE domain containing 4

1

20

High-throughput

0.437

High

399253

CFAD
Complement factor D

1

1

High-throughput

0.437

High

1298385

MT21E
Protein-lysine methyltransferase METTL21E

1

5

High-throughput

0.437

High

1317941

FNDC5
Fibronectin type III domain-containing protein 5

1

1

High-throughput

0.437

High


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Last updated: 11Aug2025