HitPredict

Interactor 1: FGFR1 (P11362)
Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Gene: FGFR1

Interactor 2: RIN1 (Q13671)
Ras and Rab interactor 1 (Ras inhibitor JC99) (Ras interaction/interference protein 1)
Gene: RIN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	12783862
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 822 Hs			1 783
+	Mm
		975150 EPHA4_MOUSE (3-783): 0: 621: 19.70		RIN1_MOUSE (1-783): 0: 686: 77.23
+	Hs
		508072 FGFR1_HUMAN (1-822): 0: 861: 100.00		RINL_HUMAN (26-635): 7.7e-95: 308: 22.42
+	Hs
		601513 FGFR2_HUMAN (1-821): 0: 803: 71.21		GAPD1_HUMAN (132-596): 4.11e-109: 365: 13.10
+	Hs
		508060 FGFR1_HUMAN (1-822): 0: 861: 100.00		TENS2_HUMAN (4-230): 1.01e-38: 157: 18.60
+	Hs
		181796 FGFR3_HUMAN (6-821): 0: 730: 61.22		SOCS1_HUMAN (49-192): 1.35e-26: 110: 24.32
+	Hs
		384858 NTRK1_HUMAN (122-769): 8.92e-140: 434: 25.96		GAPD1_HUMAN (132-596): 4.11e-109: 365: 13.10
+	Hs
		872663 EPHA4_HUMAN (3-783): 0: 620: 19.44		TENS3_HUMAN (28-227): 4.82e-43: 171: 20.37
+	Hs
		385682 NTRK1_HUMAN (122-769): 8.92e-140: 434: 25.96		RABX5_HUMAN (285-630): 4.38e-97: 312: 14.21
+	Hs
		872709 EPHA4_HUMAN (3-783): 0: 620: 19.44		SLAP2_HUMAN (19-170): 5.44e-26: 109: 18.64
+	Hs
		434221 RET_HUMAN (384-774): 2.63e-98: 332: 45.77		RINL_HUMAN (26-635): 7.7e-95: 308: 22.42
+	Hs
		674461 UFO_HUMAN (8-815): 1.07e-155: 479: 21.98		TENS2_HUMAN (4-230): 1.01e-38: 157: 18.60
+	Hs
		181803 UFO_HUMAN (8-815): 1.07e-155: 479: 21.98		SOCS1_HUMAN (49-192): 1.35e-26: 110: 24.32
+	Hs
		738272 FLT3_HUMAN (462-754): 8.76e-79: 276: 43.47		TENS1_HUMAN (10-225): 3.96e-37: 152: 16.46
+	Hs
		181766 CSF1R_HUMAN (212-750): 1.67e-79: 277: 32.28		SOCS1_HUMAN (49-192): 1.35e-26: 110: 24.32
+	Mm
		193337 CSF1R_MOUSE (209-769): 3.02e-79: 277: 32.53		SOCS1_MOUSE (49-192): 1.01e-26: 110: 24.32
+	Hs
		181810 FLT3_HUMAN (462-754): 8.76e-79: 276: 43.47		SOCS1_HUMAN (49-192): 1.35e-26: 110: 24.32
+	Hs
		181846 TIE2_HUMAN (484-771): 3.85e-69: 250: 45.52		SOCS1_HUMAN (49-192): 1.35e-26: 110: 24.32
+	Mm
		193336 KIT_MOUSE (20-579): 8.18e-45: 176: 21.53		SOCS1_MOUSE (49-192): 1.01e-26: 110: 24.32
+	Hs
		1251968 V5YQL4_HUMAN (1-250): 4.05e-20: 98.2: 18.27		RIN3_HUMAN (9-369): 5.23e-38: 154: 23.21