Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC
Interactor 2: OTU7B (Q6GQQ9)
OTU domain-containing protein 7B (EC 3.4.19.12) (Cellular zinc finger anti-NF-kappa-B protein) (Cezanne) (Zinc finger A20 domain-containing protein 1) (Zinc finger protein Cezanne)
Gene: OTUD7B
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.983 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 29576527, 27182664, 31699778, 31937588, 33141564, 34642328, 38803224, 22179831, 25752577, 25723849, 26876099, 27732584, 20622874, 23827681 |
| Identification Methods | pull down, proximity labelling technology, affinity chromatography technology, enzymatic study, x-ray crystallography |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | OTU~ubiquitin, ubiquitin~zf-A20 |
| Common GO terms | GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol |
| Homologous interactions | 11 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
