HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: RN145 (Q96MT1)
RING finger protein 145 (EC 2.3.2.27)
Gene: RNF145

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	29374057
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	ubiquitin~zf-RING_2
Common GO terms	GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 663
+	Hs
		508813 UBC_HUMAN (1-685): 0: 857: 100.00		AMFR_HUMAN (271-661): 9.16e-61: 216: 15.11
+	Hs
		220468 UBC_HUMAN (1-685): 0: 857: 100.00		RNF13_HUMAN (422-659): 1.1e-29: 123: 16.33
+	Hs
		508233 UBC_HUMAN (1-685): 0: 857: 100.00		GOLI_HUMAN (464-581): 3.92e-26: 113: 20.66
+	Hs
		508893 UBC_HUMAN (1-685): 0: 857: 100.00		RN115_HUMAN (518-595): 4.81e-12: 69.5: 32.53
+	Sc
		509741 UBI4P_YEAST (381-685): 4.09e-126: 380: 95.74		HRD1_YEAST (280-656): 5.03e-37: 147: 13.24
+	At
		1020702 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		ATL1_ARATH (464-662): 3.19e-26: 113: 14.29
+	Hs
		987263 RS27A_HUMAN (609-684): 7.26e-41: 148: 100.00		AMFR_HUMAN (271-661): 9.16e-61: 216: 15.11
+	Mm
		509315 UBC_MOUSE (1-108): 2.12e-30: 129: 90.74		AMFR_MOUSE (271-661): 1.79e-61: 218: 15.37
+	Hs
		987097 RS27A_HUMAN (609-684): 7.26e-41: 148: 100.00		GOLI_HUMAN (464-581): 3.92e-26: 113: 20.66
+	Hs
		507229 UBB_HUMAN (1-77): 1.15e-26: 110: 98.70		RNF43_HUMAN (399-655): 5.38e-33: 137: 13.64
+	Hs
		507263 UBB_HUMAN (1-77): 1.15e-26: 110: 98.70		GOLI_HUMAN (464-581): 3.92e-26: 113: 20.66
+	Mm
		509263 UBC_MOUSE (1-108): 2.12e-30: 129: 90.74		RN115_MOUSE (518-579): 2.07e-12: 70.6: 36.36