HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: EPN1 (Q9Y6I3)
Epsin-1 (EH domain-binding mitotic phosphoprotein) (EPS-15-interacting protein 1)
Gene: EPN1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.60	0.747

Property	Details
Experiments	16497222, 40437099, 28190767, 31699778, 38803224, 19285159, 23314748
Identification Methods	pull down, cross-linking study, protein array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 576
+	Rn
		312079 UBC_RAT (1-637): 0: 779: 98.90		EPN1_RAT (1-576): 4.67e-91: 293: 94.27
+	Hs
		508607 UBC_HUMAN (1-685): 0: 857: 100.00		EPN3_HUMAN (1-571): 4.34e-55: 198: 40.16
+	Hs
		329418 UBC_HUMAN (1-685): 0: 857: 100.00		EPN2_HUMAN (1-566): 1.15e-53: 194: 38.02
+	Dm
		509798 UBIQP_DROME (1-610): 0: 759: 99.84		Q7KU90_DROME (1-571): 7.17e-58: 209: 31.51
+	Hs
		508167 UBC_HUMAN (1-685): 0: 857: 100.00		OTOG_HUMAN (190-573): 2.45e-15: 82: 10.91
+	Rn
		1224311 UBC_RAT (1-637): 0: 779: 98.90		SYNJ1_RAT (246-575): 3.38e-15: 81.2: 14.67
+	Sc
		509777 UBI4P_YEAST (381-685): 4.09e-126: 380: 95.74		ENT1_YEAST (3-228): 7.21e-62: 212: 36.73
+	Sc
		509721 UBI4P_YEAST (381-685): 4.09e-126: 380: 95.74		ENT2_YEAST (3-538): 1.04e-58: 208: 19.59
+	Dm
		1269718 R9PY16_DROME (457-685): 1.03e-83: 268: 90.39		Q7KU90_DROME (1-571): 7.17e-58: 209: 31.51
+	At
		1167656 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		EPN2_ARATH (2-574): 1.97e-39: 156: 21.89
+	Hs
		987285 RS27A_HUMAN (609-684): 7.26e-41: 148: 100.00		EPN1_HUMAN (1-576): 7.54e-90: 290: 100.00
+	Hs
		116892 RS27A_HUMAN (609-684): 7.26e-41: 148: 100.00		I6L9I8_HUMAN (1-288): 1.6e-92: 288: 54.43
+	Mm
		509138 UBC_MOUSE (1-108): 2.12e-30: 129: 90.74		EPN1_MOUSE (1-576): 2.07e-88: 286: 94.44
+	Mm
		509179 UBC_MOUSE (1-108): 2.12e-30: 129: 90.74		EPN2_MOUSE (1-562): 6.34e-64: 221: 41.91
+	Hs
		987208 RS27A_HUMAN (609-684): 7.26e-41: 148: 100.00		EPN3_HUMAN (1-571): 4.34e-55: 198: 40.16
+	Hs
		329441 RS27A_HUMAN (609-684): 7.26e-41: 148: 100.00		EPN2_HUMAN (1-566): 1.15e-53: 194: 38.02
+	Hs
		507364 UBB_HUMAN (1-77): 1.15e-26: 110: 98.70		EPN3_HUMAN (1-571): 4.34e-55: 198: 40.16