HitPredict

Interactor 1: PYC (P11498)
Pyruvate carboxylase, mitochondrial (EC 6.4.1.1) (Pyruvic carboxylase) (PCB)
Gene: PC

Interactor 2: ARF4 (P18085)
ADP-ribosylation factor 4
Gene: ARF4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35844135
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1178 Hs			1 180
+	Hs
		513564 PYC_HUMAN (1-1178): 0: 1462: 100.00		ARF5_HUMAN (1-180): 4.28e-74: 221: 90.00
+	Hs
		513558 PYC_HUMAN (1-1178): 0: 1462: 100.00		ARF3_HUMAN (1-180): 2.97e-67: 204: 78.89
+	Hs
		950605 ACACA_HUMAN (1-746): 1.06e-175: 573: 22.40		ARF5_HUMAN (1-180): 4.28e-74: 221: 90.00
+	Hs
		574662 ACACA_HUMAN (1-746): 1.06e-175: 573: 22.40		ARF4_HUMAN (1-180): 5.6e-70: 211: 100.00
+	Hs
		135983 ACACB_HUMAN (1-742): 5.49e-175: 572: 23.27		ARF4_HUMAN (1-180): 5.6e-70: 211: 100.00
+	Sc
		424334 PYR1_YEAST (19-420): 2.78e-58: 223: 16.83		ARF2_YEAST (1-180): 5.78e-67: 204: 71.67
+	Hs
		398248 PCCA_HUMAN (1065-1178): 1.27e-34: 144: 30.44		ARF5_HUMAN (1-180): 4.28e-74: 221: 90.00
+	Hs
		398222 PCCA_HUMAN (1065-1178): 1.27e-34: 144: 30.44		ARF4_HUMAN (1-180): 5.6e-70: 211: 100.00
+	Hs
		950686 MCCA_HUMAN (1085-1178): 3.52e-27: 121: 29.00		ARF5_HUMAN (1-180): 4.28e-74: 221: 90.00
+	Hs
		574734 MCCA_HUMAN (1085-1178): 3.52e-27: 121: 29.00		ARF4_HUMAN (1-180): 5.6e-70: 211: 100.00
+	Hs
		950543 MCCA_HUMAN (1085-1178): 3.52e-27: 121: 29.00		ARF1_HUMAN (1-180): 2.16e-67: 204: 80.56