Interactor 1: PABP1 (P11940)
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)
Gene: PABPC1

Interactor 2: TNR6A (Q8NDV7)
Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (EMSY interactor protein) (GW182 autoantigen) (Protein GW1) (Glycine-tryptophan protein of 182 kDa)
Gene: TNRC6A

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.929

The method score is based on:

Property Details
Experiments 21984185, 23172285, 21063388, 20181956, 28877994
Identification Methods pull down, affinity chromatography technology, x-ray crystallography, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PABP~TNRC6-PABC_bdg
Common GO terms GO:0003723 - RNA binding
GO:0005829 - cytosol
GO:0060213 - positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 636
Hs

1 1962
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024