Interactor 1: SIR4 (P11978)
Regulatory protein SIR4 (Silent information regulator 4)
Gene: SIR4

Interactor 2: HST1 (P53685)
NAD-dependent protein deacetylase HST1 (EC 2.3.1.286) (Homologous to SIR2 protein 1) (Regulatory protein SIR2 homolog 1)
Gene: HST1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 21690292
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DUF592~SIR4_SID, SIR2~SIR4_SID
Common GO terms GO:0030466 - silent mating-type cassette heterochromatin formation
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1358
Sc

1 503
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024