HitPredict

Interactor 1: SIR4 (P11978)
Regulatory protein SIR4 (Silent information regulator 4)
Gene: SIR4

Interactor 2: UBP10 (P53874)
Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.4.19.12) (Deubiquitinating enzyme 10) (Disrupter of telomere silencing protein 4) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10)
Gene: UBP10

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.717

Property	Details
Experiments	10490600, 26149687, 16554755, 29288197, 31515872
Identification Methods	two hybrid, affinity chromatography technology, pull down, x-ray crystallography, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000781 - chromosome, telomeric region GO:0031509 - subtelomeric heterochromatin formation
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 1358 Sc			1 792
+	Sc
		516902 SIR4_YEAST (1-1358): 0: 2508: 100.00		UBP3_YEAST (16-734): 4.12e-79: 275: 15.39