HitPredict

Interactor 1: GRAA (P12544)
Granzyme A (EC 3.4.21.78) (CTL tryptase) (Cytotoxic T-lymphocyte proteinase 1) (Fragmentin-1) (Granzyme-1) (Hanukkah factor) (H factor) (HF)
Gene: GZMA

Interactor 2: GRAA (P12544)
Granzyme A (EC 3.4.21.78) (CTL tryptase) (Cytotoxic T-lymphocyte proteinase 1) (Fragmentin-1) (Granzyme-1) (Hanukkah factor) (H factor) (HF)
Gene: GZMA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.922

The method score is based on:

Property Details
Experiments 19059912, 10666226, 12819769, 18951048, 12819770
Identification Methods pull down, comigration in non denaturing gel electrophoresis, x-ray crystallography
Interaction Type direct interaction, physical association, covalent binding

The annotation score is based on:

Property Details
Interacting Pfam domains Trypsin~Trypsin
Common GO terms GO:0001772 - immunological synapse
GO:0004252 - serine-type endopeptidase activity
GO:0005615 - extracellular space
GO:0005634 - nucleus
GO:0005737 - cytoplasm
and 14 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 262
Hs

1 262
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024