HitPredict

Interactor 1: TCPA (P12612)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha)
Gene: TCP1

Interactor 2: PP2A1 (P23594)
Serine/threonine-protein phosphatase PP2A-1 catalytic subunit (EC 3.1.3.16)
Gene: PPH21

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.521

Property	Details
Experiments	37968396, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 559 Sc			1 369
+	Hs
		826603 TCPG_HUMAN (4-555): 0: 575: 29.53		PP2AB_HUMAN (62-369): 0: 534: 73.70
+	Hs
		826610 TCPG_HUMAN (4-555): 0: 575: 29.53		PP2AA_HUMAN (62-369): 0: 532: 74.03
+	Hs
		573203 TCPA_HUMAN (9-556): 0: 569: 62.23		PP2AB_HUMAN (62-369): 0: 534: 73.70
+	Sc
		618772 TCPG_YEAST (7-552): 0: 537: 28.75		PP2A1_YEAST (1-369): 0: 566: 100.00
+	Hs
		573211 TCPA_HUMAN (9-556): 0: 569: 62.23		PP2AA_HUMAN (62-369): 0: 532: 74.03
+	Hs
		826591 TCPG_HUMAN (4-555): 0: 575: 29.53		PP4C_HUMAN (67-369): 0: 524: 59.87
+	Sc
		618836 TCPG_YEAST (7-552): 0: 537: 28.75		PP2A2_YEAST (1-369): 0: 561: 87.80
+	Sc
		618781 TCPH_YEAST (1-555): 0: 531: 31.00		PP2A1_YEAST (1-369): 0: 566: 100.00
+	Hs
		573192 TCPA_HUMAN (9-556): 0: 569: 62.23		PP4C_HUMAN (67-369): 0: 524: 59.87
+	Sc
		618845 TCPH_YEAST (1-555): 0: 531: 31.00		PP2A2_YEAST (1-369): 0: 561: 87.80
+	Hs
		915267 TCPH_HUMAN (4-556): 0: 555: 31.78		PP2AB_HUMAN (62-369): 0: 534: 73.70
+	Hs
		930969 TCPH_HUMAN (4-556): 0: 555: 31.78		PP2AA_HUMAN (62-369): 0: 532: 74.03
+	Hs
		890997 TCPH_HUMAN (4-556): 0: 555: 31.78		PP4C_HUMAN (67-369): 0: 524: 59.87
+	Sc
		519892 TCPA_YEAST (1-559): 0: 589: 100.00		PP11_YEAST (71-369): 1.43e-131: 380: 55.08
+	Hs
		135401 TCPG_HUMAN (4-555): 0: 575: 29.53		PPP6_HUMAN (70-366): 3.1e-129: 374: 55.89
+	Hs
		135360 TCPA_HUMAN (9-556): 0: 569: 62.23		PPP6_HUMAN (70-366): 3.1e-129: 374: 55.89
+	Hs
		135491 TCPH_HUMAN (4-556): 0: 555: 31.78		PPP6_HUMAN (70-366): 3.1e-129: 374: 55.89
+	Sc
		594322 TCPG_YEAST (7-552): 0: 537: 28.75		PP11_YEAST (71-369): 1.43e-131: 380: 55.08
+	Sc
		594334 TCPH_YEAST (1-555): 0: 531: 31.00		PP11_YEAST (71-369): 1.43e-131: 380: 55.08
+	Hs
		135397 TCPE_HUMAN (17-552): 0: 530: 29.31		PPP6_HUMAN (70-366): 3.1e-129: 374: 55.89