Interactor 1: TCPA (P12612)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha)
Gene: TCP1

Interactor 2: TCPB (P39076)
T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta)
Gene: CCT2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.857

The method score is based on:

Property Details
Experiments 7908441, 37968396, 21701561
Identification Methods coimmunoprecipitation, pull down, affinity chromatography technology, x-ray crystallography
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Cpn60_TCP1~Cpn60_TCP1
Common GO terms GO:0005524 - ATP binding
GO:0005832 - chaperonin-containing T-complex
GO:0006457 - protein folding
GO:0016887 - ATP hydrolysis activity
GO:0051082 - unfolded protein binding
and 2 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 559
Sc

1 527
+ Bt
+ Bt
+ Hs
+ Hs
+ At
+ Mm
+ Bt
+ Bt
+ Sc
+ Hs
+ Sc
+ Hs
+ Bt
+ Hs
+ Hs
+ Hs
+ Sc

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Last updated: 15 Jul 2024