HitPredict

Interactor 1: HMDH1 (P12683)
3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 (HMG-CoA reductase 1) (EC 1.1.1.34)
Gene: HMG1

Interactor 2: NSG1 (P38837)
Protein NSG1 (INSIG homolog 1)
Gene: NSG1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.793

The method score is based on:

Property Details
Experiments 16093310, 37968396
Identification Methods ubiquitin reconstruction, affinity chromatography technology, protein complementation assay
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains INSIG~Sterol-sensing
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0034399 - nuclear periphery
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1054
Sc

1 291
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024