Protein: CLP1
Polyribonucleotide 5'-hydroxyl-kinase Clp1 (EC 2.7.1.78) (Polyadenylation factor Clp1) (Polynucleotide kinase Clp1) (Pre-mRNA cleavage complex II protein Clp1)

Gene: CLP1
Organism: Homo sapiens
Interactions: 65
UniProt ID: Q92989

Gene Ontology (top 5):
GO:0000214 - tRNA-intron endonuclease complex
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

321866

PCF11
Pre-mRNA cleavage complex 2 protein Pcf11

2

4

Small-scale

0.799

High

1280121

SEN54
tRNA-splicing endonuclease subunit Sen54

5

0

Small-scale

0.683

High

1335481

SEN2
tRNA-splicing endonuclease subunit Sen2

4

0

Small-scale

0.661

High

1358895

SEN15
tRNA-splicing endonuclease subunit Sen15

4

0

Small-scale

0.661

High

1371169

CE164
Centrosomal protein of 164 kDa

2

1

High-throughput

0.606

High

1371160

SEN34
tRNA-splicing endonuclease subunit Sen34

2

0

Small-scale

0.585

High

1371171

AMMR1
Nuclear protein AMMECR1

2

0

High-throughput

0.585

High

242496

PRKN
E3 ubiquitin-protein ligase parkin

2

1

High-throughput

0.584

High

643537

PIMT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase

2

0

High-throughput

0.580

High

701201

PSB5
Proteasome subunit beta type-5

2

0

High-throughput

0.580

High

1335562

DGLB
Diacylglycerol lipase-beta

2

0

High-throughput

0.580

High

1371158

SNF8
Vacuolar-sorting protein SNF8

2

0

High-throughput

0.580

High

1371163

FTO
Alpha-ketoglutarate-dependent dioxygenase FTO

2

0

High-throughput

0.580

High

396658

ESR1
Estrogen receptor

2

5

High-throughput

0.571

High

1118547

TBB2A
Tubulin beta-2A chain

1

1

High-throughput

0.536

High

1371161

TBB2B
Tubulin beta-2B chain

1

1

High-throughput

0.536

High

1232501

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.515

High

62254

MBLC1
Metallo-beta-lactamase domain-containing protein 1

1

0

High-throughput

0.513

High

1111163

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.513

High

1371165

CARF
CDKN2A-interacting protein

1

0

High-throughput

0.513

High

1371170

KLK5
Kallikrein-5

1

0

High-throughput

0.513

High

1371172

TACC3
Transforming acidic coiled-coil-containing protein 3

1

0

High-throughput

0.513

High

230380

CREB3
Cyclic AMP-responsive element-binding protein 3

1

0

Small-scale

0.504

High

1100630

DHRS2
Dehydrogenase/reductase SDR family member 2, mitochondrial

1

0

High-throughput

0.493

High

894072

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.481

High

422784

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

130566

SPT5H
Transcription elongation factor SPT5

1

1

High-throughput

0.479

High

143167

NFIB
Nuclear factor 1 B-type

1

3

High-throughput

0.479

High

474180

NFIC
Nuclear factor 1 C-type

1

4

High-throughput

0.479

High

520259

ANDR
Androgen receptor

1

5

High-throughput

0.479

High

621702

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.479

High

1087917

NFIA
Nuclear factor 1 A-type

1

5

High-throughput

0.479

High

1133580

NFIX
Nuclear factor 1 X-type

1

5

High-throughput

0.479

High

1160236

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

1

Small-scale

0.479

High

1329067

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

1

Small-scale

0.479

High

1329795

SIR6
NAD-dependent protein deacylase sirtuin-6

1

1

High-throughput

0.479

High

1366950

ESR2
Estrogen receptor beta

1

5

High-throughput

0.479

High

1371159

CI072
Guanine nucleotide exchange factor C9orf72

1

1

High-throughput

0.479

High

1371164

XRN2
5'-3' exoribonuclease 2

1

2

High-throughput

0.479

High

1371166

CPSF2
Cleavage and polyadenylation specificity factor subunit 2

1

3

Small-scale

0.479

High

905457

HCFC1
Host cell factor 1

1

0

Small-scale

0.460

High

228336

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

Small-scale

0.458

High

246829

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.458

High

294119

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

848915

MAGAB
Melanoma-associated antigen 11

1

0

Small-scale

0.458

High

905000

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

967898

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

0

High-throughput

0.458

High

1109959

HDAC1
Histone deacetylase 1

1

0

High-throughput

0.458

High

1161345

HIF1A
Hypoxia-inducible factor 1-alpha

1

0

High-throughput

0.458

High

1336809

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

0

Small-scale

0.458

High

1351112

SP7
Transcription factor Sp7

1

0

High-throughput

0.458

High

1363934

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.458

High

1371167

NXF1
Nuclear RNA export factor 1

1

0

High-throughput

0.458

High

1371168

RCOR1
REST corepressor 1

1

0

High-throughput

0.458

High

1254922

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

214100

FGF16
Fibroblast growth factor 16

2

0

High-throughput

0.316

High

569263

YJU2B
Probable splicing factor YJU2B

2

0

High-throughput

0.316

High

1009274

PRR3
Proline-rich protein 3

2

0

High-throughput

0.316

High

1131210

MESD
LRP chaperone MESD

2

0

High-throughput

0.316

High

231333

EFNA2
Ephrin-A2

1

0

High-throughput

0.279

Low

608320

EGLN
Endoglin

1

0

High-throughput

0.279

Low

647390

IDS
Iduronate 2-sulfatase

1

0

High-throughput

0.279

Low

1371157

SNX21
Sorting nexin-21

1

0

High-throughput

0.279

Low

1371162

GRB1L
GREB1-like protein

1

0

High-throughput

0.279

Low

1332484

POC5
Centrosomal protein POC5

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025