Protein: NOL9
Polynucleotide 5'-hydroxyl-kinase NOL9 (EC 2.7.1.78) (Nucleolar protein 9)

Gene: NOL9
Organism: Homo sapiens
Interactions: 138
UniProt ID: Q5SY16

Gene Ontology (top 5):
GO:0000448 - cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000460 - maturation of 5.8S rRNA
GO:0003723 - RNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1211369

LAS1L
Ribosomal biogenesis protein LAS1L

4

2

Small-scale

0.881

High

1211315

PELP1
Proline-, glutamic acid- and leucine-rich protein 1

4

1

Small-scale

0.694

High

1211341

WDR18
WD repeat-containing protein 18

4

2

High-throughput

0.694

High

134054

IPO5
Importin-5

3

1

High-throughput

0.675

High

1211360

TEX10
Testis-expressed protein 10

4

0

Small-scale

0.661

High

372237

MYC
Myc proto-oncogene protein

4

0

High-throughput

0.648

High

1211350

SENP3
Sentrin-specific protease 3

3

0

High-throughput

0.634

High

251219

RNBP6
Ran-binding protein 6

2

1

High-throughput

0.628

High

288670

NPM3
Nucleoplasmin-3

2

1

High-throughput

0.628

High

447098

NPM
Nucleophosmin

2

1

High-throughput

0.611

High

1058063

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

2

0

High-throughput

0.602

High

1133977

ZN638
Zinc finger protein 638

2

0

High-throughput

0.602

High

1211327

K0232
Uncharacterized protein KIAA0232

2

0

High-throughput

0.602

High

1211354

JPH1
Junctophilin-1

2

0

High-throughput

0.602

High

1211368

DCAF1
DDB1- and CUL4-associated factor 1

2

0

High-throughput

0.602

High

978989

RS6
Small ribosomal subunit protein eS6

2

1

High-throughput

0.584

High

1048873

REL
Proto-oncogene c-Rel

1

1

High-throughput

0.573

High

396275

ESR1
Estrogen receptor

2

5

High-throughput

0.571

High

916669

PPP5
Serine/threonine-protein phosphatase 5

1

1

High-throughput

0.554

High

587101

ITF2
Transcription factor 4

1

0

High-throughput

0.549

High

1068227

AHNK
Neuroblast differentiation-associated protein AHNAK

1

0

High-throughput

0.549

High

258923

DNJA2
DnaJ homolog subfamily A member 2

1

2

High-throughput

0.536

High

635326

IMDH1
Inosine-5'-monophosphate dehydrogenase 1

1

1

High-throughput

0.536

High

833125

MNDA
Myeloid cell nuclear differentiation antigen

1

2

High-throughput

0.536

High

1006458

SRPK2
SRSF protein kinase 2

1

1

High-throughput

0.536

High

1211323

PHF10
PHD finger protein 10

1

3

High-throughput

0.536

High

1211340

FYCO1
FYVE and coiled-coil domain-containing protein 1

1

1

High-throughput

0.536

High

1211346

FOXQ1
Forkhead box protein Q1

1

1

High-throughput

0.536

High

504840

H2AB1
Histone H2A-Bbd type 1

1

0

High-throughput

0.513

High

549003

KPSH1
Serine/threonine-protein kinase H1

1

0

High-throughput

0.513

High

625434

CSK22
Casein kinase II subunit alpha'

1

0

High-throughput

0.513

High

846754

GRK6
G protein-coupled receptor kinase 6

1

0

High-throughput

0.513

High

872408

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.513

High

884114

SRP09
Signal recognition particle 9 kDa protein

1

0

High-throughput

0.513

High

1066339

RBBP4
Histone-binding protein RBBP4

1

0

High-throughput

0.513

High

1091296

FOXL1
Forkhead box protein L1

1

0

High-throughput

0.513

High

1144018

TEBP
Prostaglandin E synthase 3

1

0

High-throughput

0.513

High

1207304

SPIN3
Spindlin-3

1

0

High-throughput

0.513

High

1211314

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1211324

PSPC1
Paraspeckle component 1

1

0

High-throughput

0.513

High

1211331

LTV1
Protein LTV1 homolog

1

0

High-throughput

0.513

High

1211334

RBM14
RNA-binding protein 14

1

0

High-throughput

0.513

High

1211367

LMBL1
Lethal(3)malignant brain tumor-like protein 1

1

0

High-throughput

0.513

High

1211370

NGN3
Neurogenin-3

1

0

High-throughput

0.513

High

1211371

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

0

High-throughput

0.513

High

964317

SUMO2
Small ubiquitin-related modifier 2

1

1

High-throughput

0.501

High

157475

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.479

High

241920

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

248311

HBP1
HMG box-containing protein 1

1

1

High-throughput

0.479

High

274616

DNJB6
DnaJ homolog subfamily B member 6

1

3

High-throughput

0.479

High

487399

PARP1
Poly [ADP-ribose] polymerase 1

1

1

High-throughput

0.479

High

626255

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

1

High-throughput

0.479

High

679183

DNJB1
DnaJ homolog subfamily B member 1

1

2

High-throughput

0.479

High

765604

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.479

High

984802

RL31
Large ribosomal subunit protein eL31

1

1

High-throughput

0.479

High

1088390

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

1

High-throughput

0.479

High

1132748

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

1

High-throughput

0.479

High

1161487

IF16
Gamma-interferon-inducible protein 16

1

2

High-throughput

0.479

High

1211310

IFIX
Pyrin and HIN domain-containing protein 1

1

2

High-throughput

0.479

High

1211319

NUP43
Nucleoporin Nup43

1

2

High-throughput

0.479

High

1211320

DNJB8
DnaJ homolog subfamily B member 8

1

3

High-throughput

0.479

High

1211325

DNJC9
DnaJ homolog subfamily C member 9

1

3

High-throughput

0.479

High

1211328

ESR2
Estrogen receptor beta

1

5

High-throughput

0.479

High

1211329

KAT6A
Histone acetyltransferase KAT6A

1

3

High-throughput

0.479

High

1211333

CI072
Guanine nucleotide exchange factor C9orf72

1

1

High-throughput

0.479

High

1211337

RING2
E3 ubiquitin-protein ligase RING2

1

2

High-throughput

0.479

High

1211338

DNJC7
DnaJ homolog subfamily C member 7

1

2

High-throughput

0.479

High

1211345

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

1

High-throughput

0.479

High

1211349

XRN2
5'-3' exoribonuclease 2

1

2

High-throughput

0.479

High

1211356

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

1

High-throughput

0.479

High

125490

LEG9
Galectin-9

1

0

High-throughput

0.458

High

129160

MEN1
Menin

1

0

High-throughput

0.458

High

140954

NOP56
Nucleolar protein 56

1

0

High-throughput

0.458

High

172909

XPO1
Exportin-1

1

0

High-throughput

0.458

High

190944

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.458

High

260058

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

277713

H2AY
Core histone macro-H2A.1

1

0

High-throughput

0.458

High

345920

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

349118

LATS1
Serine/threonine-protein kinase LATS1

1

0

High-throughput

0.458

High

400961

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

412059

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

413979

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

430013

JUN
Transcription factor Jun

1

0

High-throughput

0.458

High

537300

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

586735

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

588873

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

643883

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.458

High

695653

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

714179

PML
Protein PML

1

0

High-throughput

0.458

High

768378

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

830881

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

879172

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

883569

CENPA
Histone H3-like centromeric protein A

1

0

High-throughput

0.458

High

979791

H4
Histone H4

1

0

High-throughput

0.458

High

980830

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

High-throughput

0.458

High

982694

RS24
Small ribosomal subunit protein eS24

1

0

High-throughput

0.458

High

1024619

VIGLN
Vigilin

1

0

High-throughput

0.458

High

1026420

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

1106943

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1107805

SQSTM
Sequestosome-1

1

0

High-throughput

0.458

High

1113315

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1211313

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1211317

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

0

High-throughput

0.458

High

1211321

SNIP1
Smad nuclear-interacting protein 1

1

0

High-throughput

0.458

High

1211322

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1211326

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

1211330

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

0

High-throughput

0.458

High

1211332

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1211335

PASK
PAS domain-containing serine/threonine-protein kinase

1

0

High-throughput

0.458

High

1211339

BARD1
BRCA1-associated RING domain protein 1

1

0

High-throughput

0.458

High

1211344

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

1211347

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

1211348

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.458

High

1211352

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1211355

ANLN
Anillin

1

0

High-throughput

0.458

High

1211357

SLX9
Ribosome biogenesis protein SLX9 homolog

1

0

Small-scale

0.458

High

1211359

AKIP
Small ribosomal subunit protein mS38

1

0

High-throughput

0.458

High

1211361

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1211362

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.458

High

1211363

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1211366

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

1130296

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

1

High-throughput

0.445

High

1211311

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1211351

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

1211342

S4A5
Electrogenic sodium bicarbonate cotransporter 4

1

0

High-throughput

0.426

High

1211358

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

1

0

High-throughput

0.426

High

1211364

DDX41
Probable ATP-dependent RNA helicase DDX41

1

0

High-throughput

0.426

High

1211312

KCTD9
BTB/POZ domain-containing protein KCTD9

2

0

High-throughput

0.328

High

1211318

SHCBP
SHC SH2 domain-binding protein 1

2

0

High-throughput

0.328

High

1211353

MRS2
Magnesium transporter MRS2 homolog, mitochondrial

2

0

High-throughput

0.328

High

334193

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

1

0

High-throughput

0.279

Low

1193583

CE022
UPF0489 protein C5orf22

1

0

High-throughput

0.279

Low

1211336

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.279

Low

1211343

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

0

High-throughput

0.279

Low

124370

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.249

Low

1025920

NDP
Norrin

1

0

Small-scale

0.249

Low

1211316

RHG24
Rho GTPase-activating protein 24

1

0

High-throughput

0.249

Low

1211365

HECD1
E3 ubiquitin-protein ligase HECTD1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025