HitPredict

Interactor 1: RRAS (P10301)
Ras-related protein R-Ras (EC 3.6.5.2) (p23)
Gene: RRAS

Interactor 2: RASF5 (Q8WWW0)
Ras association domain-containing protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL)
Gene: RASSF5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.80	0.648

Property	Details
Experiments	11857081
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	C1_1~Ras, RA~Ras
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 218 Hs			1 418
+	Mm
		1204186 RASH_MOUSE (42-217): 1.68e-56: 179: 53.41		RASF5_MOUSE (3-418): 0: 574: 85.10
+	Hs
		165130 RASM_HUMAN (21-199): 4.3e-56: 179: 56.11		RASF5_HUMAN (1-418): 0: 574: 100.00
+	Hs
		374815 RASH_HUMAN (42-217): 1.68e-56: 179: 53.41		RASF5_HUMAN (1-418): 0: 574: 100.00
+	Mm
		1204187 RAP1B_MOUSE (30-208): 2.97e-55: 176: 50.00		RASF5_MOUSE (3-418): 0: 574: 85.10
+	Hs
		959373 RAP1B_HUMAN (30-208): 2.97e-55: 176: 50.00		RASF5_HUMAN (1-418): 0: 574: 100.00
+	Hs
		375778 RASK_HUMAN (42-213): 5.57e-54: 172: 51.74		RASF5_HUMAN (1-418): 0: 574: 100.00
+	Hs
		982109 RAP1A_HUMAN (30-192): 5.2e-54: 172: 51.83		RASF5_HUMAN (1-418): 0: 574: 100.00
+	Hs
		374960 RASH_HUMAN (42-217): 1.68e-56: 179: 53.41		RASF1_HUMAN (87-410): 5.17e-145: 418: 45.10
+	Hs
		374474 RASH_HUMAN (42-217): 1.68e-56: 179: 53.41		RASF2_HUMAN (223-418): 2.6e-56: 190: 26.96
+	Hs
		375300 RASK_HUMAN (42-213): 5.57e-54: 172: 51.74		RASF2_HUMAN (223-418): 2.6e-56: 190: 26.96